DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2064 and dhrs13a.2

DIOPT Version :9

Sequence 1:	NP_610310.2	Gene:	CG2064 / 35708	FlyBaseID:	FBgn0033205	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001004641.1	Gene:	dhrs13a.2 / 447903	ZFINID:	ZDB-GENE-040912-69	Length:	318	Species:	Danio rerio

Alignment Length:	308	Identity:	137/308 - (44%)
Similarity:	192/308 - (62%)	Gaps:	13/308 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 IYFLKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDI 87
            :..::...:..|.....|.|||..|:||.||||||.|||::|.||..|.||||:..:.|.|..||
Zfish    16 VVLVETLFKKSKCNGSADVTGKTAIITGGNTGIGKATALDLAGRGMRVILACRNQKKAEAAINDI 80

  Fly    88 IKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNH 152
            .|.|.:..:...||||.||.|:|.|.:.|.|.:.:|.:||||||::...:  |:||:.::.||||
Zfish    81 KKATGSDEVLFMELDLGSLKSVRAFAETFLKSESRLDLLINNAGLVADGR--TEDGFGIEFGVNH 143

  Fly   153 IGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYDEG-------LAYSQSKLA 210
            :||||||.||||.||.|..:|::.:||:|:..|.|:...|.:.|....|       .||..|||.
Zfish   144 LGHFLLTCLLLDRLKESPAARVITLSSMAYRWGRIDFDSLITTKDLGSGRYSWQFFQAYCNSKLC 208

  Fly   211 NVLFTRELAKRLEGSGVTVNALHPGVVDTELARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTS 275
            |||||.||||||:|:.||..::|||||.|||:||.:.:|    |.|::|:...|...||:||||:
Zfish   209 NVLFTHELAKRLKGTSVTCYSVHPGVVKTELSRNVSLWQ----KVFIEPVARLLFLDPKTGAQTT 269

  Fly   276 IYAALDPELKNISGLYFSDCKPKPVASGALDDKVAKFLWAESEKWTGL 323
            ::.|:...:::.||.|||.|..:.|.:.|.||.||:.||..||:.:||
Zfish   270 LHCAVQEGIEHFSGRYFSCCAVEEVGAKAKDDAVARKLWQISERLSGL 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	134/288 (47%)
CG2064	NP_610310.2	NADB_Rossmann	43..317	CDD:304358	130/280 (46%)
dhrs13a.2	NP_001004641.1	PRK06197	33..318	CDD:235737	136/291 (47%)
dhrs13a.2	NP_001004641.1	NADB_Rossmann	36..311	CDD:304358	130/280 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830