DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2064 and dhrs13l1

DIOPT Version :9

Sequence 1:	NP_610310.2	Gene:	CG2064 / 35708	FlyBaseID:	FBgn0033205	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_991211.1	Gene:	dhrs13l1 / 402945	ZFINID:	ZDB-GENE-040426-1907	Length:	318	Species:	Danio rerio

Alignment Length:	314	Identity:	147/314 - (46%)
Similarity:	190/314 - (60%)	Gaps:	24/314 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 YFL--KEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKD 86
            ||:  :.::....||......||..||||.||||||.||..:|.||..|.||||...:.|:|.|:
Zfish    14 YFIVHRIFVHRKTFTGTAKLYGKTVIVTGGNTGIGKATATALAVRGARVILACRSKQKGEEAAKE 78

  Fly    87 IIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVN 151
            |..|:.|.::...:|||:|..|||.|.:.|.|.:|:|.:||||||:....:  |:||..:.||||
Zfish    79 IRTESGNDDVIFMQLDLASQKSIRSFAETFLKTEPRLDLLINNAGLAAAGR--TEDGIGMILGVN 141

  Fly   152 HIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEK-----SYDEGL--AYSQSKL 209
            |||.||||||||:.||..||||:|.|||..|..|:|:...:|:.|     |.|..|  ||:.|||
Zfish   142 HIGPFLLTNLLLERLKECAPSRVVNVSSCGHDLGTIDFDCINTHKKLGLGSSDGDLFRAYTHSKL 206

  Fly   210 ANVLFTRELAKRLEGSGVTVNALHPGVVDTELARN---W--AFFQTNLVKFFLKPMIWPLLKTPK 269
            .|||||.||||||||:.||..:||||.|.:||.|:   |  ....|.:.|||        ...|.
Zfish   207 CNVLFTHELAKRLEGTNVTCYSLHPGSVRSELGRDITEWHARVLLTVVSKFF--------ATDPV 263

  Fly   270 SGAQTSIYAALDPELKNISGLYFSDCKPKPVASGALDDKVAKFLWAESEKWTGL 323
            |||||::|.:|...::::||.|||||:...|.:.|.||.|||.||..|||..|:
Zfish   264 SGAQTTLYCSLQDGIEHLSGRYFSDCQLVQVKAEARDDGVAKKLWEVSEKLCGM 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	142/293 (48%)
CG2064	NP_610310.2	NADB_Rossmann	43..317	CDD:304358	139/285 (49%)
dhrs13l1	NP_991211.1	PRK06197	35..316	CDD:235737	142/290 (49%)
dhrs13l1	NP_991211.1	NADB_Rossmann	35..311	CDD:304358	139/285 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830