Protein Alignment Rdh1 and Wwox

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Alignment Length: 292
• Identity: 110/292 - (37%)
• Similarity: 164/292 - (56%)
• Gaps: 25/292 - (8%)

  Fly    40 DETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFSR--ELD 102
            |..|:..::||||.|||.|||..:|..|..:..|||:.:..|.|.:.|.:|........|  .||
  Fly   118 DLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALD 182

  Fly   103 LSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDVLK 167
            ||||.|:::||:..|:....:..||.||||...|.|.|.||.|....|:|:.||.|| |.|:.|.
  Fly   183 LSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLT-LQLETLF 246

  Fly   168 NSAPSRIVVVSSLAHARGSINVADL------NSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSG 226
            : ..:||:|:||.:|...::.|.:|      ...:.|...:||:.:||.||||.:|||:|.:..|
  Fly   247 D-YKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWKQRG 310

  Fly   227 VTVNALHPG-VVDTELARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISGL 290
            ::|.:|||| :|.::|:||:.|::      .|..::.|..|:.:..|.||||.|...||..:|||
  Fly   311 ISVFSLHPGNMVSSDLSRNYWFYR------LLFAIVRPFTKSLQQAAATSIYCATANELTGLSGL 369

  Fly   291 YFSD---CKPKPVA-SGALDDKVAKFLWAESE 318
            ||::   |:|..:: |.||..:    ||..||
  Fly   370 YFNNCFFCEPSKLSKSAALQQQ----LWKLSE 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	107/286 (37%)
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	109/289 (38%)