Protein Alignment Rdh1 and Mfe2

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_573109.1
• Gene: Mfe2 / 32582
• FlyBaseID: FBgn0030731
• Length: 598
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 83/340 - (24%)
• Similarity: 130/340 - (38%)
• Gaps: 86/340 - (25%)

  Fly    33 GKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIF 97
            ||...|    |:|.:||||..|:|:|.||..|.||..|.:            .|:....:.....
  Fly     6 GKLRYD----GRVAVVTGAGAGLGREYALLFAERGAKVVV------------NDLGGTHSGDGAS 54

  Fly    98 SRELDLSSLDSIRK-----------FVDGFK------KEQPKLHVLINNAGVMR---CPKTLTKD 142
            .|..|: .:|.|||           .:||.|      |...::.:|:||||::|   ..||..:|
  Fly    55 QRAADI-VVDEIRKAGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQD 118

  Fly   143 GYELQLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYDEGLAYS-- 205
             :.|...|:..|.|..|......:|.....||::.||.:...|:....:..:.|....|||.:
  Fly   119 -WNLVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVA 182

  Fly   206 -----QSKLANVLFTRELAKRLEG--SGVTVNALHPGVVDTELA--------RNWAFFQTNLVKF 255
                 .:.|.||:.....::..||  ..:..|.|.|.::...:|        .|.::.::
  Fly   183 IEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAPVVAYLCHESCEDNGSYIES----- 242

  Fly   256 FLKPMIWPLLKTPKSGAQTSIY------AALDPELKN-ISGLYFSDCKPKPVASGALDDKVAKFL 313
                         .:|..|.::      |.|.|.|.: ::..|..|     |.|...|...||.|
  Fly   243 -------------AAGWATKLHMVRGKGAVLRPSLDDPVTIEYVKD-----VWSNVTDMSKAKHL 289

  Fly   314 WAESE-KWTGLDKLE 327
            .|.:| ..|.|:.||
  Fly   290 GAIAEASGTLLEVLE 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	75/317 (24%)
Mfe2	NP_573109.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	63/284 (22%)
		PLN02864	315..598	CDD:178455