DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2064 and CG3842

DIOPT Version :9

Sequence 1:	NP_610310.2	Gene:	CG2064 / 35708	FlyBaseID:	FBgn0033205	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001259270.1	Gene:	CG3842 / 31576	FlyBaseID:	FBgn0029866	Length:	406	Species:	Drosophila melanogaster

Alignment Length:	333	Identity:	177/333 - (53%)
Similarity:	222/333 - (66%)	Gaps:	26/333 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IFIDCLLSPLIMWPATIGVGIYFLKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRG 67
            ||:..|...|.||         .|::.:||..:.|.....|||.||||.||||||||.||:|:||
  Fly    43 IFLIVLGILLFMW---------LLRKCIQGPAYRKANRIDGKVVIVTGCNTGIGKETVLELAKRG 98

  Fly    68 GTVYLACRDMNRCEKARKDIIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGV 132
            ..||:||||..|||.||.||:..:.||.:|:|.|||.||.|:|.||:.||.|:.:|.:|||||||
  Fly    99 ARVYMACRDPGRCEAARLDIMDRSRNQQLFNRTLDLGSLQSVRNFVERFKAEESRLDILINNAGV 163

  Fly   133 MRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKS 197
            |.||:|||.||:|.|.||||:|||||||||||.||:|:|||||||||.||..|.||..||.|||:
  Fly   164 MACPRTLTADGFEQQFGVNHLGHFLLTNLLLDRLKHSSPSRIVVVSSAAHLFGRINREDLMSEKN 228

  Fly   198 YDEGL-AYSQSKLANVLFTRELAKRLEGSGVTVNALHPGVVDTELARNWA---FFQTNLVK---- 254
            |.:.. |||||||||:|||.:|:..|:.:|||||..|||||.||:.|:::   :.:|.|.|
  Fly   229 YSKFFGAYSQSKLANILFTLKLSTILKDTGVTVNCCHPGVVRTEINRHFSGPGWMKTALQKGSLY 293

  Fly   255 FFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISGLYFSDCKPKPVASGALDDKVAKFLWAESEK 319
            ||         ||||:||||.:..||||:|:..:|.|:|||...|:.....:.:.|.:||.||||
  Fly   294 FF---------KTPKAGAQTQLRLALDPQLEGSTGGYYSDCMRWPLFPWVRNMQTADWLWRESEK 349

  Fly   320 WTGLDKLE 327
            ..||..||
  Fly   350 LLGLPPLE 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	163/289 (56%)
CG2064	NP_610310.2	NADB_Rossmann	43..317	CDD:304358	159/281 (57%)
CG3842	NP_001259270.1	FabG	71..319	CDD:223959	150/256 (59%)
CG3842	NP_001259270.1	NADB_Rossmann	74..347	CDD:304358	159/281 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448977
Domainoid	1	1.000	171	1.000	Domainoid score	I1148
eggNOG	1	0.900	-	-		E2759_KOG1208
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I1212
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm6476
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	P	PTHR24320
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
	12	11.830