Protein Alignment Rdh1 and Rdh12

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001101507.1
• Gene: Rdh12 / 314264
• RGDID: 1310462
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 302
• Identity: 153/302 - (50%)
• Similarity: 198/302 - (65%)
• Gaps: 14/302 - (4%)

  Fly    26 LKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKE 90
            ::::..||..|......|||.::||||||||||||.|:||||..||:||||:.:.|.|..:|..:
  Rat    22 IRKFFAGGVCTTKVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRAD 86

  Fly    91 TNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGH 155
            |.|..:..|:||||...|||.|.:||..|:.|||:||||||||.||.:.|.||:|...||||:||
  Rat    87 TKNSQVLVRKLDLSDTKSIRTFAEGFLAEEKKLHILINNAGVMMCPYSKTVDGFETHFGVNHLGH 151

  Fly   156 FLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYDEGLAYSQSKLANVLFTRELAK 220
            ||||.|||..||.|||:|::.:||:||..|.|...||.|:|.|..|.|||.||||||||||||||
  Rat   152 FLLTYLLLGRLKESAPARVINLSSVAHLGGKIRFHDLQSKKRYCSGFAYSHSKLANVLFTRELAK 216

  Fly   221 RLEGSGVTVNALHPGVVDTELARNWAFFQTNLVKFFLKPMIW----PLLKTPKSGAQTSIYAALD 281
            ||:|:|||...:|||.|.:|:.|:          .||..::|    |..|:|..|||||::.||:
  Rat   217 RLQGTGVTAYVVHPGCVLSEITRH----------SFLMCLLWRLFSPFFKSPWQGAQTSLHCALE 271

  Fly   282 PELKNISGLYFSDCKPKPVASGALDDKVAKFLWAESEKWTGL 323
            ..|:.:||.||||||...|:..|.:.|.|:.||..|.:..|:
  Rat   272 EGLEPLSGKYFSDCKRTWVSPRARNKKTAERLWNVSCELLGI 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	148/277 (53%)
Rdh12	NP_001101507.1	Rossmann-fold NAD(P)(+)-binding proteins	39..307	CDD:473865	148/277 (53%)