Protein Alignment Rdh1 and Dhrs13

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001385697.1
• Gene: Dhrs13 / 303275
• RGDID: 1305508
• Length: 375
• Species: Rattus norvegicus
• Alignment Length: 286
• Identity: 130/286 - (45%)
• Similarity: 186/286 - (65%)
• Gaps: 13/286 - (4%)

  Fly    43 GKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFSRELDLSSLD 107
            |:..:|||||:||||.||||:||||..|.||||...|.|.|..|:.:|:.|..:....|||:||.
  Rat    36 GRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLT 100

  Fly   108 SIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDVLKNSAPS 172
            |::.|...|...:|:|.:||:|||:..|.:  |::.:.|.|.|||:|.||||:|||..|::.|||
  Rat   101 SVQAFATAFLSSEPRLDILIHNAGISSCGR--TRETFNLLLRVNHVGPFLLTHLLLPRLRSCAPS 163

  Fly   173 RIVVVSSLAHARGSINVADLNSE-KSYDEGL-AYSQSKLANVLFTRELAKRLEGSGVTVNALHPG 235
            |:|:|||.||.||.::...|:.. ..:.:.| ||:.||||||||.||||.:|||:|||..|.|||
  Rat   164 RVVIVSSAAHRRGRLDFTRLDCPVVGWQQELRAYADSKLANVLFARELATQLEGTGVTCYAAHPG 228

  Fly   236 VVDTELARNWAFFQTNL---VKFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISGLYFSDCKP 297
            .|::||      |..:|   ::..|:|:.|.:|:.|:.||||.:|.||...::.:||.||::|..
  Rat   229 PVNSEL------FLRHLPGWLRPILRPLAWLVLRAPQGGAQTPLYCALQEGIEPLSGRYFANCHV 287

  Fly   298 KPVASGALDDKVAKFLWAESEKWTGL 323
            :.|::.|.||:.|..||..::|..||
  Rat   288 EEVSAAARDDQAAHRLWKVTKKLAGL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	127/278 (46%)
Dhrs13	NP_001385697.1	retinol-DH_like_SDR_c_like	36..304	CDD:212492	125/275 (45%)