DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2064 and Wwox

DIOPT Version :9

Sequence 1:NP_610310.2 Gene:CG2064 / 35708 FlyBaseID:FBgn0033205 Length:330 Species:Drosophila melanogaster
Sequence 2:XP_006255728.1 Gene:Wwox / 292041 RGDID:1309927 Length:414 Species:Rattus norvegicus


Alignment Length:302 Identity:122/302 - (40%)
Similarity:179/302 - (59%) Gaps:23/302 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 EYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETN 92
            |.:||..|      ||||.:|||||:|||.|||...|..|..|.||||:|:|..:|...|::|.:
  Rat   115 EILQGRDF------TGKVVLVTGANSGIGFETAKSFALHGAHVILACRNMSRASEAVSRILEEWH 173

  Fly    93 NQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFL 157
            ...:.:..|||:.|.|::.|.:.||.:...||:|:.|||....|.:|||||.|....|||:|||.
  Rat   174 KAKVEAMTLDLAVLRSVQHFAEAFKAKNVPLHILVCNAGTFALPWSLTKDGLETTFQVNHLGHFY 238

  Fly   158 LTNLLLDVLKNSAPSRIVVVSSLAH-------ARGSINVADLN-SEKSYDEGLAYSQSKLANVLF 214
            |..||.|||..|||:|::||||.:|       :.|.::::.|: |...|...|||::|||.|:||
  Rat   239 LVQLLQDVLCRSAPARVIVVSSESHRFTDINDSSGKLDLSRLSLSSSDYWAMLAYNRSKLCNILF 303

  Fly   215 TRELAKRLEGSGVTVNALHPG-VVDTELARN-WAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIY 277
            :.||.:.|...|||.|||||| ::.:.:.|| |.:       ..|..:..|..|:.:.||.|::|
  Rat   304 SNELHRLLSPRGVTSNALHPGNMMFSAIHRNSWVY-------KLLFTLARPFTKSMQQGAATTVY 361

  Fly   278 AALDPELKNISGLYFSDCKPKPVASGALDDKVAKFLWAESEK 319
            .|:.|||:.:.|:||::|.....:..|.:::.|:.||..||:
  Rat   362 CAVAPELEGLGGMYFNNCCRCLPSEEAQNEETARALWELSER 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2064NP_610310.2 PRK06197 40..322 CDD:235737 118/290 (41%)
NADB_Rossmann 43..317 CDD:304358 115/283 (41%)
WwoxXP_006255728.1 WW 18..47 CDD:395320
WW 60..90 CDD:238122
human_WWOX_like_SDR_c-like 124..407 CDD:187669 117/287 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000061
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100091
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X72
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.810

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