Protein Alignment Rdh1 and Hsd17b13

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_932147.2
• Gene: Hsd17b13 / 243168
• MGIID: 2140804
• Length: 304
• Species: Mus musculus
• Alignment Length: 307
• Identity: 82/307 - (26%)
• Similarity: 127/307 - (41%)
• Gaps: 65/307 - (21%)

  Fly    19 IGVGIYFLKEYMQGGKF---TKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNR- 79
            :||.||...|.:.  ||   .:....||:..::|||..|||:.||.|.|::...:.|  .|:|:
Mouse    11 VGVIIYSYLESLV--KFFIPRRRKSVTGQTVLITGAGHGIGRLTAYEFAKQKSRLVL--WDINKR 71

  Fly    80 -----CEKARK--DIIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPK 137
                 .:|.||  .::      ::|  .:|.|:...|...||..|:|...:.:::||||.:....
Mouse    72 GVEETADKCRKLGAVV------HVF--VVDCSNRAEIYNSVDQVKREVGDVEIVVNNAGAIYPAD 128

  Fly   138 TLTKDGYEL--QLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYDE 200
            .|:....|:  ...||.:|||.:...||..:.......||.|:|:. ..|.|...
Mouse   129 LLSAKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVC-GHGVIPYL---------- 182

  Fly   201 GLAYSQSKLANVLFTRELAKRLE---GSGVTVNALHPGVVDTELARNWAFFQTNLVKFFLKPMIW 262
             :.|..||.|.|.|.|.|...|:   .:|:..:.|.|..|:|...:|            ....:|
Mouse   183 -IPYCSSKFAAVGFHRALTAELDTLGKTGIQTSCLCPVFVNTGFTKN------------PSTRLW 234

  Fly   263 PLLKTPKSGAQTSIYAALD-------PELKNIS-----GLYFSDCKP 297
            |:|: |:..|::.|...|.       |...|||     |..||...|
Mouse   235 PVLE-PEEVARSLINGILTNKKMIFVPSYINISLILEKGPGFSSKHP 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	74/280 (26%)
Hsd17b13	NP_932147.2	17beta-HSDXI-like_SDR_c	38..269	CDD:187598	69/265 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..304		2/5 (40%)