Protein Alignment Rdh1 and E04F6.15

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_495501.1
• Gene: E04F6.15 / 184041
• WormBaseID: WBGene00017131
• Length: 319
• Species: Caenorhabditis elegans
• Alignment Length: 296
• Identity: 102/296 - (34%)
• Similarity: 159/296 - (53%)
• Gaps: 25/296 - (8%)

  Fly    40 DETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFSRELDLS 104
            |.:||.|.:||..:|||.|||..:..:|..|.:..|:....|.::|.::.||.|..|...:.||:
 Worm    25 DLSGKTFAITGTTSGIGVETAKALILKGAHVVMINRNYTASEASKKSLLIETPNAQIDIVQCDLN 89

  Fly   105 SLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDVLKNS 169
            ||.|::|..|.:.:::..||.||.||||....:..|.||:|...|:||:.||:|...||.||:.|
 Worm    90 SLSSVKKAADEYLEQKWPLHGLILNAGVFGPSEKTTSDGFEAHFGINHLAHFILIKELLPVLRES 154

  Fly   170 APSRIVVVSSLAHARGSIN-----VADLNS----EKSYDEGLAYSQSKLANVLFTRELAKRLEGS 225
            ||||||:|:|:......:.     |..|::    |.:......|::||:.|:|...:|.:....:
 Worm   155 APSRIVIVTSMLSKHTCVKPDSRIVEKLDTLCPKEATQWYFRLYAKSKMCNILTAFKLHRDEFKN 219

  Fly   226 GVTVNALHPGV-VDTELARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISG 289
            .::|.|:|||. |.|:|.|::..:.   :..||.   .|..|....||.||:|.|:.||:|.:||
 Worm   220 RISVYAVHPGSGVRTDLHRDFGLWS---IADFLS---IPFTKNASQGAATSLYCAVHPEVKELSG 278

  Fly   290 LYFSDC------KPKPVASGALDDKVAKFLWAESEK 319
            .|:..|      ..|.|:.   |:::.:.||..|||
 Worm   279 KYWESCWDDEKNLDKKVSR---DEELQEALWEHSEK 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	98/289 (34%)
E04F6.15	NP_495501.1	retinol-DH_like_SDR_c_like	28..306	CDD:212492	96/286 (34%)