Protein Alignment Rdh1 and DC2.5

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_503155.4
• Gene: DC2.5 / 183970
• WormBaseID: WBGene00017082
• Length: 337
• Species: Caenorhabditis elegans
• Alignment Length: 307
• Identity: 102/307 - (33%)
• Similarity: 157/307 - (51%)
• Gaps: 41/307 - (13%)

  Fly    40 DETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFSRELDLS 104
            |.:||.:.:||..:|:|.|||.....:|..:.:..|:....|..::.::.||.:..|...:.|||
 Worm    42 DLSGKTYAITGTTSGVGTETARAFILKGAHIVMINRNYAASETLKQSLLCETPDARIDIVQCDLS 106

  Fly   105 SLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDVLKNS 169
            ||.|::|..:.:..::..||.||.||||:...:..|.|.:|...|:||:.||||...||.||::|
 Worm   107 SLASVKKTAEEYLTKKWPLHGLILNAGVLGRKEKTTADRFEAHFGINHLAHFLLIKELLPVLRSS 171

  Fly   170 APSRIVVVSSLAHARGSINVADLNSEKSYDEGLA--------------YSQSKLANVLFTRELAK 220
            ||||||::||......||     |.:...:|.|.              |::||:.|:|...:|.:
 Worm   172 APSRIVILSSTLSKFTSI-----NPDSKIEEKLGTLCPKNATEWYYRLYAKSKMCNMLIAFKLHR 231

  Fly   221 RLEGSGVTVNALHPG-VVDTELARN---WAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYAALD 281
            ....:|::|.::||| .|.|.|.|:   |:.|.      ||.   .|..|....||.||:|.|:.
 Worm   232 DEFENGISVYSVHPGSAVRTNLHRDVPFWSIFN------FLS---IPFTKNASQGAATSLYCAVH 287

  Fly   282 PELKNISGLYFSDCKPKPVASGALDDKVAK------FLWAESEKWTG 322
            ||::.:||.|:..|....:   .||:|||:      .||..||:..|
 Worm   288 PEVQELSGRYWESCWDDEL---NLDEKVARDEELQEALWEYSEELVG 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	98/297 (33%)
DC2.5	NP_503155.4	retinol-DH_like_SDR_c_like	45..323	CDD:212492	96/294 (33%)