Protein Alignment Rdh1 and dhs-3

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001122509.1
• Gene: dhs-3 / 172603
• WormBaseID: WBGene00000967
• Length: 309
• Species: Caenorhabditis elegans
• Alignment Length: 323
• Identity: 76/323 - (23%)
• Similarity: 125/323 - (38%)
• Gaps: 77/323 - (23%)

  Fly     8 LLSPLI----MWPATIGVGIYFLKEYMQGGKFTKD--TDETGKVFIVTGANTGIGKETALEIARR 66
            ||||.:    .|..      |:.|.:.......|:  ...:|:..::||:.:|:|:..|.|..:.
 Worm     6 LLSPQLEIASQWDG------YYEKTFEVSDHVHKEIILKVSGQTVLITGSGSGLGRLMAFEFGKL 64

  Fly    67 GGTVYLACRDMNRCEKARKDIIKETNNQNIFSR--ELDLSSLDSIRKFVDGFKKEQPKLHVLINN 129
            |..:.|  .|:|  |:..|:.:||.....:.::  .:|||....|.:..|..|.|..|:.:|:||
 Worm    65 GARLVL--WDIN--EQGNKETLKELEAMGVEAKAYTVDLSEYKEINRTADLVKSEVGKVDILVNN 125

  Fly   130 AGV------MRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSIN 188
            ||:      ::||..|...    .:.||....|..|...|..:..|....||.::|:|   |...
 Worm   126 AGIVTGKKLLQCPDELMVK----TVSVNTNALFFTTKNFLPGMLESNKGHIVTIASMA---GKCG 183

  Fly   189 VADLNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSGVTVNALHPGVVDTELARNWAFFQTNLV 253
            ||.|....:...|.......||:.|:.  |.|.::.:.|....::.|:.| .:|..|
 Worm   184 VAGLVDYCASKHGAVGFNDSLASELYA--LKKDVKTTVVCPIYINTGMFD-GIATKW-------- 237

  Fly   254 KFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISGLYFSDCKPKPVASGALDDK----VAKF 312
                 |.:.|:               |.||       |..||    :....|.|:    :.||
 Worm   238 -----PTLLPI---------------LSPE-------YVVDC----IMEAVLTDRAFLAIPKF 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	68/282 (24%)
dhs-3	NP_001122509.1	17beta-HSDXI-like_SDR_c	43..284	CDD:187598	67/280 (24%)