Protein Alignment CG2064 and DHRS13

DIOPT Version :9

• Sequence 1: NP_610310.2
• Gene: CG2064 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_653284.2
• Gene: DHRS13 / 147015
• HGNCID: 28326
• Length: 377
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 130/287 - (45%)
• Similarity: 178/287 - (62%)
• Gaps: 15/287 - (5%)

  Fly    43 GKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFSRELDLSSLD 107
            |:..:|||||:||||.||||:||||..|.||||...|.|.|..|:.:|:.|..:....|||:||.
Human    36 GRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLA 100

  Fly   108 SIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDVLKNSAPS 172
            |:|.|...|...:|:|.:||:|||:..|.:  |::.:.|.|.|||||.||||:|||..||..|||
Human   101 SVRAFATAFLSSEPRLDILIHNAGISSCGR--TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPS 163

  Fly   173 RIVVVSSLAHARGSINVADLNSEKS--YDEGLAYSQSKLANVLFTRELAKRLEGSGVTVNALHPG 235
            |:|||:|.||.||.::...|:....  ..|..||:.:|||||||.||||.:||.:|||..|.|||
Human   164 RVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPG 228

  Fly   236 VVDTEL----ARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISGLYFSDCK 296
            .|::||    ...|       ::..|:|:.|.:|:.|:.||||.:|.||...::.:||.||::|.
Human   229 PVNSELFLRHVPGW-------LRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCH 286

  Fly   297 PKPVASGALDDKVAKFLWAESEKWTGL 323
            .:.|...|.||:.|..||..|::..||
Human   287 VEEVPPAARDDRAAHRLWEASKRLAGL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	128/284 (45%)
		NADB_Rossmann	43..317	CDD:304358	127/279 (46%)
DHRS13	NP_653284.2	retinol-DH_like_SDR_c_like	36..304	CDD:212492	125/276 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..377		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730