Protein Alignment Rdh1 and Rdh14

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_076186.1
• Gene: Rdh14 / 105014
• MGIID: 1920402
• Length: 334
• Species: Mus musculus
• Alignment Length: 298
• Identity: 149/298 - (50%)
• Similarity: 196/298 - (65%)
• Gaps: 22/298 - (7%)

  Fly    43 GKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKE-----------TNNQNI 96
            ||..::||||:|:|:.||.|:.|.|..|.:.|||..|.|:|...:.:|           |:.| :
Mouse    44 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGTDGQ-L 107

  Fly    97 FSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNL 161
            ..:||||:||.|:|.|.....:|:|:|.||||||||..||.|.|:||:|:|.||||:||||||||
Mouse   108 VVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGVNHLGHFLLTNL 172

  Fly   162 LLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSG 226
            ||.:||:|||||||||||..:..|.||..|||||:||::...||:|||||:|||||||:||||:.
Mouse   173 LLGLLKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTN 237

  Fly   227 VTVNALHPGVVDTELARNWAFFQTNLVKFFLKPMI----WPLLKTPKSGAQTSIYAALDPELKNI 287
            ||||.||||:|.|.|.|:..      :....:|:.    |...|||..|||||||.|..|:::.:
Mouse   238 VTVNVLHPGIVRTNLGRHIH------IPLLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDVEGV 296

  Fly   288 SGLYFSDCKPKPVASGALDDKVAKFLWAESEKWTGLDK 325
            ||.||.|||.:.:...|:|:.||:.||..||...|:.|
Mouse   297 SGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	145/288 (50%)
Rdh14	NP_076186.1	Rossmann-fold NAD(P)(+)-binding proteins	44..326	CDD:473865	145/288 (50%)