Protein Alignment Rdh1 and hsd17b3

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: XP_012827001.1
• Gene: hsd17b3 / 101730254
• XenbaseID: XB-GENE-986068
• Length: 302
• Species: Xenopus tropicalis
• Alignment Length: 263
• Identity: 58/263 - (22%)
• Similarity: 112/263 - (42%)
• Gaps: 39/263 - (14%)

  Fly     3 IFIDCLLSPLIMWPATIGVGIYFLKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRG 67
            :|:..|::.|.:.....|. :.:|.::::|..........|:..:||||..||||..:.|:|.||
 Frog     5 LFVVGLITCLYLTVKFFGF-LMYLFQHLRGVLPQSFFQSLGEWAVVTGAGDGIGKAYSTELANRG 68

  Fly    68 GTVYLACRDMNRCEKARKDIIKETNNQNIFSRELDLSSLDSIRKFV-DGFKKEQPKLHVLINNAG 131
            ..:.:..|.:.:.:....| |:::..:|:...:.|.:. |:|.:.: :|.|  ..|:.:||||.|
 Frog    69 MNIVMISRTLEKMQAVAMD-IEQSTGKNVKIIQADFTK-DNIYEHIEEGLK--GLKIGILINNVG 129

  Fly   132 VMRCPKTLT----KDGYELQLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLA-------HARG 185
            ::..|....    .|..:..:..|......:|.::|..::......|:.:||..       :|
 Frog   130 MLHNPDPCRFLSGPDNDKNVINCNITSTIKMTRIILKQMEKRKSGLILNISSAVGRFPCPLYA-- 192

  Fly   186 SINVADLNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSGVTVNALHPGVVDTELARNWAFFQT 250
                             .||.||.....|::.|....:..|:.:.|:.|..|.|.:.||   .:|
 Frog   193 -----------------VYSASKAFVTTFSKALQAEYKSKGIIIQAVTPYGVSTPMTRN---ART 237

  Fly   251 NLV 253
            |.:
 Frog   238 NAI 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	52/223 (23%)
hsd17b3	XP_012827001.1	17beta-HSD1_like_SDR_c	44..281	CDD:187614	52/223 (23%)