DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2064 and si:dkey-73n8.3

DIOPT Version :9

Sequence 1:	NP_610310.2	Gene:	CG2064 / 35708	FlyBaseID:	FBgn0033205	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001186991.1	Gene:	si:dkey-73n8.3 / 100150965	ZFINID:	ZDB-GENE-141219-27	Length:	296	Species:	Danio rerio

Alignment Length:	284	Identity:	141/284 - (49%)
Similarity:	188/284 - (66%)	Gaps:	7/284 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFS 98
            :::.|....||..||||||||||||||.::|.||..|.|||||:.:.|:|..||.::..|.|:..
Zfish    11 RWSSDVRLDGKTAIVTGANTGIGKETAKDLANRGARVILACRDLVKAEQAASDISRDVENANVVV 75

  Fly    99 RELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNLLL 163
            |:|||:...||.:|.:.....:..||:|||||||..||.:.|.||:|.|.||||:|||.||.||:
Zfish    76 RKLDLADTKSICEFAELIYNTEKSLHLLINNAGVAICPYSTTVDGFETQFGVNHLGHFFLTFLLI 140

  Fly   164 DVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSGVT 228
            |:||:|||||::.||||.|..|.|:..||||||:|....||.||||||:|||||||.|:|..||.
Zfish   141 DLLKHSAPSRVINVSSLVHPMGKIHFEDLNSEKNYHPVKAYVQSKLANILFTRELASRVEELGVR 205

  Fly   229 VNALHPGVVDTELARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISGLYFS 293
            |.|:.||:|:|::.|:    ....|:||:|...: ::|||..||.|::|.||.|:|.  :|.|:|
Zfish   206 VYAVDPGLVNTDITRH----LMKPVQFFVKTFGF-MIKTPAEGAYTTLYCALTPDLP--TGSYYS 263

  Fly   294 DCKPKPVASGALDDKVAKFLWAES 317
            :|.....:..|.||..|..|||.|
Zfish   264 NCAVASCSRAAKDDNSASKLWAVS 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	140/278 (50%)
CG2064	NP_610310.2	NADB_Rossmann	43..317	CDD:304358	139/273 (51%)
si:dkey-73n8.3	NP_001186991.1	PRK06197	19..295	CDD:235737	140/276 (51%)
si:dkey-73n8.3	NP_001186991.1	NADB_Rossmann	20..287	CDD:304358	139/273 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9897
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm6476
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.020