Protein Alignment CG2065 and CBR1

DIOPT Version :10

• Sequence 1: NP_610309.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001748.1
• Gene: CBR1 / 873
• HGNCID: 1548
• Length: 277
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 73/284 - (25%)
• Similarity: 116/284 - (40%)
• Gaps: 66/284 - (23%)

  Fly    16 VFIVTGANTGIGKETVLEIAKR-GGTVYMACRDMNRCEKARQDIIRETNNQNIFSRELDLSSLES 79
            |.:|||.|.|||...|.::.:. .|.|.:..||:.|.:.|.|.:..|..:...  .:||:..|:|
Human     7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRF--HQLDIDDLQS 69

  Fly    80 IRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLLLDVLKKTAP-- 142
            ||......:||...|.||:||||:..  :......|.:|..|....:|..|.   ||..:..|
Human    70 IRALRDFLRKEYGGLDVLVNNAGIAF--KVADPTPFHIQAEVTMKTNFFGTR---DVCTELLPLI 129

  Fly   143 ---SRIVNVSSLVHTQGFIKTADLNSEKSYSR-------IG----------------------AY 175
               .|:|||||::..:.....:....:|..|.       :|                      ||
Human   130 KPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAY 194

  Fly   176 SQSKLA----NVLFTRELAKRLEGTGVTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLLWVLF 236
            ..:|:.    :.:..|:|:::.:|..:..|:..||.|.|:::       .|.|.
Human   195 GVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMA-------GPKAT----------- 241

  Fly   237 KTPRNGAQTTLYAALDPALKDVSG 260
            |:|..||:|.:|.||.|  .|..|
Human   242 KSPEEGAETPVYLALLP--PDAEG 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_610309.1	Rossmann-fold NAD(P)(+)-binding proteins	14..288	CDD:473865	73/284 (26%)
CBR1	NP_001748.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	73/284 (26%)