Protein Alignment CG2065 and PBR1

DIOPT Version :10

• Sequence 1: NP_610309.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_014218.2
• Gene: PBR1 / 855540
• SGDID: S000005125
• Length: 407
• Species: Saccharomyces cerevisiae
• Alignment Length: 364
• Identity: 98/364 - (26%)
• Similarity: 152/364 - (41%)
• Gaps: 87/364 - (23%)

  Fly    14 GKVFIVTGANT-GIGKETVLEIAKRGGTVYMACRDMNR-----CEKARQDIIRETNNQNIFSREL 72
            |||::||||.: |:|.....::|:.|..:.:..|:::.     ||:.|:    :|.|:.||..:.
Yeast    53 GKVYLVTGATSQGMGTSVAYKMAELGAQLIILTREVDEWVTEWCEELRE----KTKNELIFVEKC 113

  Fly    73 DLSSLESIRKFAAGF-----KKEQDKLHVLINNAGVMHCP------RTLTKDGFEMQLGVNHMGH 126
            |||:|..|||||..:     .:..|.:.|:..:......|      |..:|||.|:|:..|::..
Yeast   114 DLSNLWEIRKFATSWLDNSPPRRLDGVIVMSGDMEPWGIPKISLPQRRSSKDGLELQIATNYVAI 178

  Fly   127 FLLTHLLLDVLKKTAPSRIVNVSSLVHTQGFIKTADLNSE-------KSYSRIGAYSQSKLANVL 184
            |.|.:||....|...|.|.|.:  ::.|.......|:|.|       |..|.:..::.|||...|
Yeast   179 FHLLNLLQPSFKAQPPDRDVRI--ILATCWLQVVGDINIEDPLWQNAKYKSALKFFASSKLQLGL 241

  Fly   185 FTRELAKRL------------EGTG--VTTNSLHPGAVDTE-----LSRNWKFLKHPFAQLLLKP 230
            ...||.:||            |.||  ||...:.||.:.:.     :|.....|......:||.|
Yeast   242 SMMELQRRLTEDIKNQKTNGAERTGKNVTITMVQPGTMRSNSLRRVISNGSVVLLIILYCILLYP 306

  Fly   231 LLWVLFKTPRNGAQTTLYAALDPA-----LKDVSGLYFSDCQ----------------------- 267
            :||:..|:.|.|.|:.|||.:.|.     |||....|.|||.
Yeast   307 ILWLFTKSGRRGDQSFLYALMTPELEEVNLKDTKVKYISDCSIVKFARKEFDDEELQKKLFDNTE 371

  Fly   268 ------PKEVSAAAQDDKTGKFLWAESEKWTGVNSTKVD 300
                  .|:|:|....:|||.    ::.|....|.::.|
Yeast   372 RDILQLEKKVAAKRNANKTGN----QNSKKKSQNKSRKD 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_610309.1	Rossmann-fold NAD(P)(+)-binding proteins	14..288	CDD:473865	95/350 (27%)
PBR1	NP_014218.2	retinol-DH_like_SDR_c_like	53..367	CDD:212492	89/319 (28%)