DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2065 and Tic32-IVa

DIOPT Version :9

Sequence 1:	NP_001260787.1	Gene:	CG2065 / 35707	FlyBaseID:	FBgn0033204	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_849428.1	Gene:	Tic32-IVa / 828442	AraportID:	AT4G23430	Length:	322	Species:	Arabidopsis thaliana

Alignment Length:	302	Identity:	123/302 - (40%)
Similarity:	174/302 - (57%)	Gaps:	14/302 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QFTKQTDETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNIFS 69
            :.|...|.||...|||||::|||.||...::.||..|.||.|:.:...|.::||:::.....:..
plant    20 EVTHGVDGTGLTAIVTGASSGIGVETARVLSLRGVHVVMAVRNTDSGAKVKEDIVKQVPGAKLDV 84

  Fly    70 RELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLLL 134
            .||||||::|:||||:.:|.....|::||||||:|.||..|:||..|:|...||:||||||.|||
plant    85 MELDLSSMQSVRKFASEYKSTGLPLNLLINNAGIMACPFMLSKDNIELQFATNHLGHFLLTKLLL 149

  Fly   135 DVLKKTA-----PSRIVNVSSLVHTQGF---IKTADLNSEKSYSRIGAYSQSKLANVLFTRELAK 191
            |.:|.|:     ..||||:||..|...:   ::...:|.:.|||.:.||.||||.|||...||.|
plant   150 DTMKSTSRESKREGRIVNLSSEAHRFSYPEGVRFDKINDKSSYSSMRAYGQSKLCNVLHANELTK 214

  Fly   192 RL--EGTGVTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPA 254
            :|  :|..:|.|||||||:.|.|.|.:    :|:..:.:..:...:.|:...||.||.|.||:|.
plant   215 QLKEDGVNITANSLHPGAIMTNLGRYF----NPYLAVAVGAVAKYILKSVPQGAATTCYVALNPQ 275

  Fly   255 LKDVSGLYFSDCQPKEVSAAAQDDKTGKFLWAESEKWTGVNS 296
            :..|||.||.|....:.....:|.:..|.:|..|.|.|...|
plant   276 VAGVSGEYFQDSNIAKPLPLVKDTELAKKVWDFSTKLTDSQS 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	121/292 (41%)
CG2065	NP_001260787.1	NADB_Rossmann	14..288	CDD:304358	116/283 (41%)
Tic32-IVa	NP_849428.1	retinol-DH_like_SDR_c_like	29..306	CDD:212492	115/280 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I1212
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D921996at2759
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm1091
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780