Protein Alignment CG2065 and DHRS12

DIOPT Version :9

• Sequence 1: NP_001260787.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001364858.1
• Gene: DHRS12 / 79758
• HGNCID: 25832
• Length: 320
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 106/261 - (40%)
• Similarity: 144/261 - (55%)
• Gaps: 34/261 - (13%)

  Fly    14 GKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNIFSRELDLSSLE 78
            |:||:|||.|:||||.|.||||||||||::.|||....|.||.:||||:.|||||...:|||..:
Human    40 GRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPK 104

  Fly    79 SIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLLLDVLKKTAPS 143
            .|.||...||:|. ||||||||||.|...|.||:||.|.....|.:|.::||..|:.||:|....
Human   105 QIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDP 168

  Fly   144 RIVNVSS---LVHTQGFIKTADLNSEKS-YSRIGAYSQSKLANVLFTRELAKRLEG-TGVTTNSL 203
            |::.|||   ||..   :.|.||.||:: :.....|:|:|...|:.|...|   :| ..:..:|:
Human   169 RVITVSSGGMLVQK---LNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWA---QGHPAIHFSSM 227

  Fly   204 HPGAVDTELSRNWKFLKHPFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVSGLYFSDCQP 268
            |||..||. .||.:.|:....:                 |||   |:..|...::. ::...|||
Human   228 HPGWADTP-DRNEQELRKVVGE-----------------AQT---ASPLPRFLEIM-MHEGKCQP 270

  Fly   269 K 269
            :
Human   271 Q 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	106/261 (41%)
		NADB_Rossmann	14..288	CDD:304358	106/261 (41%)
DHRS12	NP_001364858.1	NADB_Rossmann	40..>235	CDD:419666	94/201 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2072
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.760