DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2065 and si:dkey-174n20.1

DIOPT Version :9

Sequence 1:	NP_001260787.1	Gene:	CG2065 / 35707	FlyBaseID:	FBgn0033204	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_005165244.1	Gene:	si:dkey-174n20.1 / 796174	ZFINID:	ZDB-GENE-030131-7890	Length:	308	Species:	Danio rerio

Alignment Length:	287	Identity:	114/287 - (39%)
Similarity:	178/287 - (62%)	Gaps:	17/287 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KQTDETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNIFSREL 72
            |:.|  ||..::||.|:||||||.:.:|.||..|.:||||..:..||.::|...::|.|:...|:
Zfish    30 KRLD--GKTVLITGGNSGIGKETAVALAMRGARVIIACRDEEKARKAVREIKARSHNMNVLHMEV 92

  Fly    73 DLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTL--TKDGFEMQLGVNHMGHFLLTHLLLD 135
            ||:::.|||:|:..|.:::.:|.:||||||:   |..|  |.|.|.|..||||:||||||:|||.
Zfish    93 DLANMRSIREFSKTFLQKEKRLDILINNAGM---PGVLDWTDDNFSMCFGVNHLGHFLLTNLLLP 154

  Fly   136 VLKKTAPSRIVNVSSLVHTQGFIKTADLNSEKSYSRIG--AYSQSKLANVLFTRELAKRLEGTGV 198
            .||:::|||::|::...:....:...|||    |:...  .|.:|||||:.||:|||:.:||.||
Zfish   155 RLKESSPSRVINLTCSSYKYQKLNFQDLN----YNLFPFFTYCRSKLANIYFTQELARMMEGKGV 215

  Fly   199 TTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVSGLYF 263
            |..::|||.|.:..:.::..|    .|:|.:.::::.|.:...||||.:|.|:...:...:|.||
Zfish   216 TAYAVHPGYVRSRWTCHFSVL----YQILAQVVMFMFFVSCEAGAQTVVYCAVSDEVLPRNGGYF 276

  Fly   264 SDCQPKEVSAAAQDDKTGKFLWAESEK 290
            :||:|..:.|.|:|....|.||..||:
Zfish   277 TDCRPAPLKAFARDSGVAKKLWEASER 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	113/284 (40%)
CG2065	NP_001260787.1	NADB_Rossmann	14..288	CDD:304358	110/277 (40%)
si:dkey-174n20.1	XP_005165244.1	PRK06197	28..304	CDD:235737	114/287 (40%)
si:dkey-174n20.1	XP_005165244.1	NADB_Rossmann	34..301	CDD:304358	110/277 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830