Protein Alignment CG2065 and Rdh12

DIOPT Version :10

• Sequence 1: NP_610309.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_084293.1
• Gene: Rdh12 / 77974
• MGIID: 1925224
• Length: 316
• Species: Mus musculus
• Alignment Length: 296
• Identity: 152/296 - (51%)
• Similarity: 198/296 - (66%)
• Gaps: 14/296 - (4%)

  Fly     3 GGQFTKQTDETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNI 67
            ||..|......|||.::|||||||||||..|:|:||..||:||||:.:.|.|..:|..:|.|..:
Mouse    28 GGVCTTNVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQV 92

  Fly    68 FSRELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHL 132
            ..|:||||..:|||.||..|..|:.|||:||||||||.||.:.|.||||...||||:||||||:|
Mouse    93 LVRKLDLSDTKSIRAFAERFLAEEKKLHILINNAGVMMCPYSKTTDGFETHFGVNHLGHFLLTYL 157

  Fly   133 LLDVLKKTAPSRIVNVSSLVHTQGFIKTADLNSEKSYSRIGAYSQSKLANVLFTRELAKRLEGTG 197
            ||:.||::||:|:||:||:.|..|.|:..||..:|.|....||..|||||:||||||||||:|||
Mouse   158 LLERLKESAPARVVNLSSIAHLIGKIRFHDLQGQKRYCSAFAYGHSKLANLLFTRELAKRLQGTG 222

  Fly   198 VTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLLWVL----FKTPRNGAQTTLYAALDPALKDV 258
            ||..::|||.|.:|::||        :.||.  |||.|    ||:...||||:|:.||...|:.:
Mouse   223 VTAYAVHPGVVLSEITRN--------SYLLC--LLWRLFSPFFKSTSQGAQTSLHCALAEDLEPL 277

  Fly   259 SGLYFSDCQPKEVSAAAQDDKTGKFLWAESEKWTGV 294
            ||.|||||:...||:.|::.||.:.||..|.:..|:
Mouse   278 SGKYFSDCKRMWVSSRARNKKTAERLWNVSCELLGI 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_610309.1	Rossmann-fold NAD(P)(+)-binding proteins	14..288	CDD:473865	147/277 (53%)
Rdh12	NP_084293.1	Rossmann-fold NAD(P)(+)-binding proteins	39..307	CDD:473865	147/277 (53%)