DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2065 and 1700003E16Rik

DIOPT Version :9

Sequence 1:	NP_001260787.1	Gene:	CG2065 / 35707	FlyBaseID:	FBgn0033204	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_082224.1	Gene:	1700003E16Rik / 71837	MGIID:	1919087	Length:	598	Species:	Mus musculus

Alignment Length:	217	Identity:	44/217 - (20%)
Similarity:	82/217 - (37%)	Gaps:	56/217 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 SRELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLL 133
            |..|.:.|.||:|..|.|.:               ::.|::..|....::|..:.......:||.
Mouse   216 SHMLAVPSKESLRSTAEGER---------------VYSPQSSLKQPQVVRLQASEKESSFGSHLS 265

  Fly   134 LDVLKKTAPSRIVNVSSL-VHTQGFIKTADLNSEKSYSRIGAYSQSKLA-----NVLFTRELAKR 192
            |:.|....|........| :.::|.:.::.:.||   |.:||.:.::.:     .||..|...|
Mouse   266 LEDLYLCMPQPDAAGDRLSLQSKGQLHSSPIGSE---SHLGALTPAEPSAFQEPEVLGERPKHK- 326

  Fly   193 LEGTGVTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPL----LWVLFKTPRNGAQTTLYAALDP 253
                   |.:|...:  :.|.|:|   ..|.|::|:..|    |.:....||
Mouse   327 -------TTTLRMDS--SRLPRHW---VRPVAEVLIPDLEVHPLEIYRGRPR------------- 366

  Fly   254 ALKDVSGLYFSDCQPKEVSAAA 275
              :..:|...|.|:.:.:|:.|
Mouse   367 --RSQAGTATSACESQALSSRA 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	44/217 (20%)
CG2065	NP_001260787.1	NADB_Rossmann	14..288	CDD:304358	44/217 (20%)
1700003E16Rik	NP_082224.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		DUF4639	6..571	CDD:292118	44/217 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	151..190
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	222..241		7/33 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	366..396		6/36 (17%)
		LamG	<436..>463	CDD:304605
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	551..571
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900