DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2065 and Rdh14

DIOPT Version :9

Sequence 1:	NP_001260787.1	Gene:	CG2065 / 35707	FlyBaseID:	FBgn0033204	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001102746.1	Gene:	Rdh14 / 500629	RGDID:	1565196	Length:	334	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	145/295 - (49%)
Similarity:	188/295 - (63%)	Gaps:	20/295 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKA----RQDIIR------ETNNQNIF 68
            ||..::||||:|:|:.|..|:.:.|..|.|.|||..|.|:|    ||::.:      :..:..:.
  Rat    44 GKTVLITGANSGLGRATAGELLRLGARVIMGCRDRARAEEAAGQLRQELGQAGGLGPDATDGQLV 108

  Fly    69 SRELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLL 133
            .:||||:||.|:|.|.....:|:.:|.||||||||..||.|.|:||||||.||||:||||||:||
  Rat   109 VKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFQCPYTKTEDGFEMQFGVNHLGHFLLTNLL 173

  Fly   134 LDVLKKTAPSRIVNVSSLVHTQGFIKTADLNSEKSYSRIGAYSQSKLANVLFTRELAKRLEGTGV 198
            |.:||.:||||||.|||.::..|.|...|||||:||::...||:|||||:|||||||.|||||.|
  Rat   174 LGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRELAHRLEGTNV 238

  Fly   199 TTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLL----WVLFKTPRNGAQTTLYAALDPALKDVS 259
            |.|.||||.|.|.|.|      |....||.:||.    |..||||..||||::|.|..|.::.||
  Rat   239 TVNVLHPGIVRTNLGR------HIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLASSPDVEGVS 297

  Fly   260 GLYFSDCQPKEVSAAAQDDKTGKFLWAESEKWTGV 294
            |.||.||:.:|:...|.|:...:.||..||...|:
  Rat   298 GRYFGDCKEEELLPKAMDESVARKLWDISEVMVGI 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	144/293 (49%)
CG2065	NP_001260787.1	NADB_Rossmann	14..288	CDD:304358	142/287 (49%)
Rdh14	NP_001102746.1	PRK06197	43..332	CDD:235737	144/293 (49%)
Rdh14	NP_001102746.1	NADB_Rossmann	44..326	CDD:304358	142/287 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730