DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2065 and CG2070

DIOPT Version :9

Sequence 1:	NP_001260787.1	Gene:	CG2065 / 35707	FlyBaseID:	FBgn0033204	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001260786.1	Gene:	CG2070 / 35706	FlyBaseID:	FBgn0033203	Length:	325	Species:	Drosophila melanogaster

Alignment Length:	295	Identity:	210/295 - (71%)
Similarity:	247/295 - (83%)	Gaps:	0/295 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQGGQFTKQTDETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQ 65
            |||||||.:|:|||:|.||||.|.|||||||||:|:||.|||||||||.:||.||::||:.||||
  Fly    30 MQGGQFTTKTNETGRVAIVTGCNQGIGKETVLELARRGATVYMACRDMKKCENARREIIKATNNQ 94

  Fly    66 NIFSRELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLT 130
            |||:|:|||.|::|||.||||||:||:|||:||||||:|.||:.||:||||||:|||||||||||
  Fly    95 NIFARQLDLCSMKSIRNFAAGFKREQNKLHILINNAGIMDCPKMLTEDGFEMQIGVNHMGHFLLT 159

  Fly   131 HLLLDVLKKTAPSRIVNVSSLVHTQGFIKTADLNSEKSYSRIGAYSQSKLANVLFTRELAKRLEG 195
            .|||||||.:||||:|.:||:.|..|.||..||||||||.|..||.|||||||||||||||||.|
  Fly   160 LLLLDVLKSSAPSRVVVLSSIAHRFGRIKRDDLNSEKSYDRKMAYCQSKLANVLFTRELAKRLSG 224

  Fly   196 TGVTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVSG 260
            ||||.|:||||.|:|||.||..||...|.:||:.|::|:..||.||||||||||||||:|:.|||
  Fly   225 TGVTVNALHPGVVNTELFRNTPFLGSWFGKLLIAPIIWIFIKTARNGAQTTLYAALDPSLEKVSG 289

  Fly   261 LYFSDCQPKEVSAAAQDDKTGKFLWAESEKWTGVN 295
            .|||||:.|.|.:|||.|...:|||||||||||:|
  Fly   290 RYFSDCKQKHVGSAAQYDDDAQFLWAESEKWTGIN 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	200/282 (71%)
CG2065	NP_001260787.1	NADB_Rossmann	14..288	CDD:304358	192/273 (70%)
CG2070	NP_001260786.1	PRK06197	41..323	CDD:235737	200/281 (71%)
CG2070	NP_001260786.1	NADB_Rossmann	43..317	CDD:304358	192/273 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I1148
eggNOG	1	0.900	-	-		E2759_KOG1208
Homologene	1	1.000	-	-		H100724
Inparanoid	1	1.050	219	1.000	Inparanoid score	I1212
Isobase	1	0.950	-	0	Normalized mean entropy	S2072
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm6476
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	P	PTHR24320
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
	13	12.850