Protein Alignment CG2065 and Dhrs13

DIOPT Version :10

• Sequence 1: NP_610309.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001385697.1
• Gene: Dhrs13 / 303275
• RGDID: 1305508
• Length: 375
• Species: Rattus norvegicus
• Alignment Length: 285
• Identity: 130/285 - (45%)
• Similarity: 183/285 - (64%)
• Gaps: 11/285 - (3%)

  Fly    14 GKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNIFSRELDLSSLE 78
            |:..:|||||:||||.|.||:|:||..|.:|||...|.|.|..|:.:|:.|..:....|||:||.
  Rat    36 GRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLT 100

  Fly    79 SIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLLLDVLKKTAPS 143
            |::.||..|...:.:|.:||:|||:..|.|  |::.|.:.|.|||:|.||||||||..|:..|||
  Rat   101 SVQAFATAFLSSEPRLDILIHNAGISSCGR--TRETFNLLLRVNHVGPFLLTHLLLPRLRSCAPS 163

  Fly   144 RIVNVSSLVHTQGFIKTADLNSEKS--YSRIGAYSQSKLANVLFTRELAKRLEGTGVTTNSLHPG 206
            |:|.|||..|.:|.:....|:....  ...:.||:.||||||||.||||.:|||||||..:.|||
  Rat   164 RVVIVSSAAHRRGRLDFTRLDCPVVGWQQELRAYADSKLANVLFARELATQLEGTGVTCYAAHPG 228

  Fly   207 AVDTELSRNWKFLKH--PFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVSGLYFSDCQPK 269
            .|::||     ||:|  .:.:.:|:||.|::.:.|:.||||.||.||...::.:||.||::|..:
  Rat   229 PVNSEL-----FLRHLPGWLRPILRPLAWLVLRAPQGGAQTPLYCALQEGIEPLSGRYFANCHVE 288

  Fly   270 EVSAAAQDDKTGKFLWAESEKWTGV 294
            ||||||:||:....||..::|..|:
  Rat   289 EVSAAARDDQAAHRLWKVTKKLAGL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_610309.1	Rossmann-fold NAD(P)(+)-binding proteins	14..288	CDD:473865	128/277 (46%)
Dhrs13	NP_001385697.1	retinol-DH_like_SDR_c_like	36..304	CDD:212492	126/274 (46%)