DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2065 and SPCC736.13

DIOPT Version :9

Sequence 1:	NP_001260787.1	Gene:	CG2065 / 35707	FlyBaseID:	FBgn0033204	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_587784.1	Gene:	SPCC736.13 / 2539566	PomBaseID:	SPCC736.13	Length:	339	Species:	Schizosaccharomyces pombe

Alignment Length:	301	Identity:	115/301 - (38%)
Similarity:	171/301 - (56%)	Gaps:	23/301 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FTKQTDETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNIFSR 70
            |....|.||||.:|||::.|||..|.||:|::|..||:|.|:..:.:|..:.|..|..:..|...
pombe    34 FNDIPDLTGKVALVTGSSGGIGYVTALELARKGAKVYLAGRNEEKYQKVMKQIHDEVRHSKIRFL 98

  Fly    71 ELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLLLD 135
            .|||...||:.:.|..|..:::|||:|:||||:|:.|..|||||:|:|:..|::.|:|.|.|||.
pombe    99 RLDLLDFESVYQAAESFIAKEEKLHILVNNAGIMNPPFELTKDGYELQIQTNYLSHYLFTELLLP 163

  Fly   136 VLKKTAPS------RIVNVSSLVHTQ---GFIKTADLNSEK----SYSRIGAYSQSKLANVLFTR 187
            .|::||..      |||:|:|:.:.|   ..|...|||...    :::|   |.|||.|.:|::.
pombe   164 TLRRTAEECRPGDVRIVHVASIAYLQAPYSGIYFPDLNLPHVLLGTFAR---YGQSKYAQILYSI 225

  Fly   188 ELAKRLEGTGVTTNSLHPGAVDTELSRNWKFLKHPFA-QLLLKPLLWVLFKTPRNGAQTTLYAAL 251
            .||||||..|:.:.|||||.:.|||:|    ....|| :||.|.:...|...|..||.|:||||.
pombe   226 ALAKRLEKYGIYSVSLHPGVIRTELTR----YSPTFALKLLEKSVFQYLLLDPIRGAMTSLYAAT 286

  Fly   252 DPAL--KDVSGLYFSDCQPKEVSAAAQDDKTGKFLWAESEK 290
            .|.:  :.::|.||:....:.:...|.||...:.|:..:.|
pombe   287 SPEISKEHLNGAYFTAIAQRGILHRAHDDAFVEELYRYTHK 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	114/296 (39%)
CG2065	NP_001260787.1	NADB_Rossmann	14..288	CDD:304358	111/289 (38%)
SPCC736.13	NP_587784.1	retinol-DH_like_SDR_c_like	42..322	CDD:212492	110/286 (38%)
SPCC736.13	NP_587784.1	adh_short	43..252	CDD:278532	87/211 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	118	1.000	Domainoid score	I1484
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I1096
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		otm47252
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
TreeFam	0	0.000	Not matched by this tool.
	10	9.790