Protein Alignment CG2065 and DHRS13

DIOPT Version :9

• Sequence 1: NP_001260787.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_653284.2
• Gene: DHRS13 / 147015
• HGNCID: 28326
• Length: 377
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 130/285 - (45%)
• Similarity: 180/285 - (63%)
• Gaps: 11/285 - (3%)

  Fly    14 GKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNIFSRELDLSSLE 78
            |:..:|||||:||||.|.||:|:||..|.:|||...|.|.|..|:.:|:.|..:....|||:||.
Human    36 GRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLA 100

  Fly    79 SIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLLLDVLKKTAPS 143
            |:|.||..|...:.:|.:||:|||:..|.|  |::.|.:.|.|||:|.||||||||..||..|||
Human   101 SVRAFATAFLSSEPRLDILIHNAGISSCGR--TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPS 163

  Fly   144 RIVNVSSLVHTQGFI--KTADLNSEKSYSRIGAYSQSKLANVLFTRELAKRLEGTGVTTNSLHPG 206
            |:|.|:|..|.:|.:  |..|.........:.||:.:|||||||.||||.:||.||||..:.|||
Human   164 RVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPG 228

  Fly   207 AVDTELSRNWKFLKH--PFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVSGLYFSDCQPK 269
            .|::||     ||:|  .:.:.||:||.|::.:.||.||||.||.||...::.:||.||::|..:
Human   229 PVNSEL-----FLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVE 288

  Fly   270 EVSAAAQDDKTGKFLWAESEKWTGV 294
            ||..||:||:....||..|::..|:
Human   289 EVPPAARDDRAAHRLWEASKRLAGL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	129/283 (46%)
		NADB_Rossmann	14..288	CDD:304358	128/277 (46%)
DHRS13	NP_653284.2	retinol-DH_like_SDR_c_like	36..304	CDD:212492	126/274 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..377		1/5 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730