Protein Alignment CG2065 and RDH12

DIOPT Version :9

• Sequence 1: NP_001260787.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_689656.2
• Gene: RDH12 / 145226
• HGNCID: 19977
• Length: 316
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 161/296 - (54%)
• Similarity: 200/296 - (67%)
• Gaps: 14/296 - (4%)

  Fly     3 GGQFTKQTDETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNI 67
            ||.........|||.::|||||||||||..|:|.||..||:||||:.:.|.|..:|..:|.|..:
Human    28 GGVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQV 92

  Fly    68 FSRELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHL 132
            ..|:||||..:|||.||.||..|:.:||:||||||||.||.:.|.||||..|||||:||||||:|
Human    93 LVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTYL 157

  Fly   133 LLDVLKKTAPSRIVNVSSLVHTQGFIKTADLNSEKSYSRIGAYSQSKLANVLFTRELAKRLEGTG 197
            ||:.||.:||:|:|||||:.|..|.|...||.|||.|||..||..||||||||||||||||:|||
Human   158 LLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAKRLQGTG 222

  Fly   198 VTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLLWVLF----KTPRNGAQTTLYAALDPALKDV 258
            |||.::|||.|.:||.|:        :.||.  |||.||    ||.|.||||:|:.||...|:.:
Human   223 VTTYAVHPGVVRSELVRH--------SSLLC--LLWRLFSPFVKTAREGAQTSLHCALAEGLEPL 277

  Fly   259 SGLYFSDCQPKEVSAAAQDDKTGKFLWAESEKWTGV 294
            ||.|||||:...||..|:::||.:.||..|.:..|:
Human   278 SGKYFSDCKRTWVSPRARNNKTAERLWNVSCELLGI 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	158/286 (55%)
		NADB_Rossmann	14..288	CDD:304358	157/277 (57%)
RDH12	NP_689656.2	retinol-DH_like_SDR_c	39..307	CDD:212495	157/277 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2072
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		otm41333
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.770