Protein Alignment CG2065 and RDH13

DIOPT Version :10

• Sequence 1: NP_610309.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001139443.1
• Gene: RDH13 / 112724
• HGNCID: 19978
• Length: 331
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 153/298 - (51%)
• Similarity: 203/298 - (68%)
• Gaps: 1/298 - (0%)

  Fly     3 GGQFTKQTDETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNI 67
            ||....:....||..|||||||||||:|.||:|:|||.:.:|||||.:||.|.:||..||.|.::
Human    27 GGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHV 91

  Fly    68 FSRELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHL 132
            .:|.|||:||:|||:|||...:|::::.:||||||||.||...|:||||||.||||:||||||:|
Human    92 NARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNL 156

  Fly   133 LLDVLKKTAPSRIVNVSSLVHTQGFIKTADLN-SEKSYSRIGAYSQSKLANVLFTRELAKRLEGT 196
            |||.||.:|||||:|:|||.|..|.|...||| ..:.|:...||.|||||.||||:||::||:|:
Human   157 LLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGS 221

  Fly   197 GVTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVSGL 261
            |||.|:||||...|||.|:.......|:...|.|:.|:|.|:|...||.:.|.|:...|.||||.
Human   222 GVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLVKSPELAAQPSTYLAVAEELADVSGK 286

  Fly   262 YFSDCQPKEVSAAAQDDKTGKFLWAESEKWTGVNSTKV 299
            ||...:.|..:..|:|::..:.|||||.:..|:.:..|
Human   287 YFDGLKQKAPAPEAEDEEVARRLWAESARLVGLEAPSV 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_610309.1	Rossmann-fold NAD(P)(+)-binding proteins	14..288	CDD:473865	147/274 (54%)
RDH13	NP_001139443.1	retinol-DH_like_SDR_c	38..313	CDD:212495	147/274 (54%)