Protein Alignment CG2065 and RDH13

DIOPT Version :9

• Sequence 1: NP_001260787.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001139443.1
• Gene: RDH13 / 112724
• HGNCID: 19978
• Length: 331
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 153/298 - (51%)
• Similarity: 203/298 - (68%)
• Gaps: 1/298 - (0%)

  Fly     3 GGQFTKQTDETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNI 67
            ||....:....||..|||||||||||:|.||:|:|||.:.:|||||.:||.|.:||..||.|.::
Human    27 GGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHV 91

  Fly    68 FSRELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHL 132
            .:|.|||:||:|||:|||...:|::::.:||||||||.||...|:||||||.||||:||||||:|
Human    92 NARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNL 156

  Fly   133 LLDVLKKTAPSRIVNVSSLVHTQGFIKTADLN-SEKSYSRIGAYSQSKLANVLFTRELAKRLEGT 196
            |||.||.:|||||:|:|||.|..|.|...||| ..:.|:...||.|||||.||||:||::||:|:
Human   157 LLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGS 221

  Fly   197 GVTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVSGL 261
            |||.|:||||...|||.|:.......|:...|.|:.|:|.|:|...||.:.|.|:...|.||||.
Human   222 GVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLVKSPELAAQPSTYLAVAEELADVSGK 286

  Fly   262 YFSDCQPKEVSAAAQDDKTGKFLWAESEKWTGVNSTKV 299
            ||...:.|..:..|:|::..:.|||||.:..|:.:..|
Human   287 YFDGLKQKAPAPEAEDEEVARRLWAESARLVGLEAPSV 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	149/283 (53%)
		NADB_Rossmann	14..288	CDD:304358	147/274 (54%)
RDH13	NP_001139443.1	retinol-DH_like_SDR_c	38..313	CDD:212495	147/274 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	251	1.000	Domainoid score	I2108
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	316	1.000	Inparanoid score	I2553
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		otm41333
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.810