DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2065 and Rdh14

DIOPT Version :9

Sequence 1:	NP_001260787.1	Gene:	CG2065 / 35707	FlyBaseID:	FBgn0033204	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_076186.1	Gene:	Rdh14 / 105014	MGIID:	1920402	Length:	334	Species:	Mus musculus

Alignment Length:	296	Identity:	148/296 - (50%)
Similarity:	191/296 - (64%)	Gaps:	22/296 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKA----RQDIIRE-------TNNQNI 67
            ||..::||||:|:|:.|..|:.:.|..|.|.|||..|.|:|    ||::.:.       |:.| :
Mouse    44 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGTDGQ-L 107

  Fly    68 FSRELDLSSLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHL 132
            ..:||||:||.|:|.|.....:|:.:|.||||||||.|||.|.|:||||||.||||:||||||:|
Mouse   108 VVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGVNHLGHFLLTNL 172

  Fly   133 LLDVLKKTAPSRIVNVSSLVHTQGFIKTADLNSEKSYSRIGAYSQSKLANVLFTRELAKRLEGTG 197
            ||.:||.:||||||.|||.::..|.|...|||||:||::...||:|||||:|||||||:|||||.
Mouse   173 LLGLLKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTN 237

  Fly   198 VTTNSLHPGAVDTELSRNWKFLKHPFAQLLLKPLL----WVLFKTPRNGAQTTLYAALDPALKDV 258
            ||.|.||||.|.|.|.|      |....||.:||.    |..||||..||||::|.|..|.::.|
Mouse   238 VTVNVLHPGIVRTNLGR------HIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDVEGV 296

  Fly   259 SGLYFSDCQPKEVSAAAQDDKTGKFLWAESEKWTGV 294
            ||.||.||:.:|:...|.|:...:.||..||...|:
Mouse   297 SGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGI 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_001260787.1	PRK06197	11..294	CDD:235737	147/294 (50%)
CG2065	NP_001260787.1	NADB_Rossmann	14..288	CDD:304358	145/288 (50%)
Rdh14	NP_076186.1	PRK06197	43..332	CDD:235737	147/294 (50%)
Rdh14	NP_076186.1	NADB_Rossmann	44..326	CDD:304358	145/288 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.760