Protein Alignment CG2065 and wwox

DIOPT Version :10

• Sequence 1: NP_610309.1
• Gene: CG2065 / 35707
• FlyBaseID: FBgn0033204
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: XP_017948987.1
• Gene: wwox / 100145151
• XenbaseID: XB-GENE-5721345
• Length: 414
• Species: Xenopus tropicalis
• Alignment Length: 289
• Identity: 121/289 - (41%)
• Similarity: 172/289 - (59%)
• Gaps: 15/289 - (5%)

  Fly    11 DETGKVFIVTGANTGIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRETNNQNIFSRELDLS 75
            |.:|||.||||||||||.||...:|..|..|.:|||::.:..:|:..|:.|.:...:....|||:
 Frog   121 DLSGKVVIVTGANTGIGFETARSLALHGTLVILACRNLQKGNEAKHKILEEWHKAKVEVMSLDLA 185

  Fly    76 SLESIRKFAAGFKKEQDKLHVLINNAGVMHCPRTLTKDGFEMQLGVNHMGHFLLTHLLLDVLKKT 140
            ||.|::.||..||.....|||||.||..:..|..||:||.||...|||:|||.|..||.|||:::
 Frog   186 SLRSVQSFAEAFKSRNLALHVLICNAAYLGGPWQLTEDGLEMTFQVNHLGHFYLVSLLQDVLQRS 250

  Fly   141 APSRIVNVSSLVHTQGFIKTA----DLN----SEKSYSRIGAYSQSKLANVLFTRELAKRLEGTG 197
            .|||:|.|||..|....||.:    |||    .:|.|..:.||::|||.|:||::||.:||...|
 Frog   251 IPSRVVVVSSESHRFTEIKDSSGKLDLNLLSPLKKDYWAMLAYNRSKLCNILFSKELNRRLSPHG 315

  Fly   198 VTTNSLHPG-AVDTELSRNWKFLKHPFAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVSGL 261
            ||:|::||| .:.:.:.|||      :...||..|:....|:.:.||.|::|.|:.|.|:.:.|:
 Frog   316 VTSNAVHPGNMMYSSIHRNW------WGYTLLFALVRPFTKSMQQGASTSVYCAVSPELEGLGGM 374

  Fly   262 YFSDCQPKEVSAAAQDDKTGKFLWAESEK 290
            ||::|.....|..||.::|...||..||:
 Frog   375 YFNNCCRCLPSQEAQREETAAALWELSER 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2065	NP_610309.1	Rossmann-fold NAD(P)(+)-binding proteins	14..288	CDD:473865	118/282 (42%)
wwox	XP_017948987.1	WW	19..47	CDD:238122
		WW	60..90	CDD:238122
		Rossmann-fold NAD(P)(+)-binding proteins	124..407	CDD:473865	120/286 (42%)