DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2070 and CBR1

DIOPT Version :9

Sequence 1:NP_001260786.1 Gene:CG2070 / 35706 FlyBaseID:FBgn0033203 Length:325 Species:Drosophila melanogaster
Sequence 2:NP_001748.1 Gene:CBR1 / 873 HGNCID:1548 Length:277 Species:Homo sapiens


Alignment Length:289 Identity:78/289 - (26%)
Similarity:124/289 - (42%) Gaps:63/289 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 VAIVTGCNQGIGKETVLELARR-GATVYMACRDMKKCENARREIIKATNNQNIFARQLDLCSMKS 108
            ||:|||.|:|||...|.:|.|. ...|.:..||:.:.:.|.:: ::|......| .|||:..::|
Human     7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQ-LQAEGLSPRF-HQLDIDDLQS 69

  Fly   109 IRNFAAGFKREQNKLHILINNAGIMDCPKMLTEDGFEMQIGVNHMGHFLLT----LLLLDVLKSS 169
            ||......::|...|.:|:|||||  ..|:.....|.:|..|....:|..|    ..||.::|..
Human    70 IRALRDFLRKEYGGLDVLVNNAGI--AFKVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQ 132

  Fly   170 APSRVVVLSSI---------------AHRFGRIKRDDL---------NSEKSYDRK-----MAYC 205
              .|||.:|||               ..|...|..::|         :::|...:|     .||.
Human   133 --GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYG 195

  Fly   206 QSKLANVLFTRELAKRLS----GTGVTVNALHPGVVNTELFRNTPFLGSWFGKLLIAPIIWIFIK 266
            .:|:...:.:|..|::||    |..:.:||..||.|.|:               :..|..   .|
Human   196 VTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTD---------------MAGPKA---TK 242

  Fly   267 TARNGAQTTLY-AALDPSLEKVSGRYFSD 294
            :...||:|.:| |.|.|..|...|::.|:
Human   243 SPEEGAETPVYLALLPPDAEGPHGQFVSE 271

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG2070NP_001260786.1 PRK06197 41..323 CDD:235737 78/289 (27%)
NADB_Rossmann 43..317 CDD:304358 78/289 (27%)
CBR1NP_001748.1 carb_red_PTCR-like_SDR_c 6..277 CDD:187585 78/289 (27%)
Glutathione binding 95..97 0/1 (0%)