DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2070 and Tic32-IVa

DIOPT Version :9

Sequence 1:	NP_001260786.1	Gene:	CG2070 / 35706	FlyBaseID:	FBgn0033203	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_849428.1	Gene:	Tic32-IVa / 828442	AraportID:	AT4G23430	Length:	322	Species:	Arabidopsis thaliana

Alignment Length:	299	Identity:	120/299 - (40%)
Similarity:	164/299 - (54%)	Gaps:	16/299 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QFTTKTNETGRVAIVTGCNQGIGKETVLELARRGATVYMACRDMKKCENARREIIKATNNQNIFA 98
            :.|...:.||..|||||.:.|||.||...|:.||..|.||.|:.......:.:|:|......:..
plant    20 EVTHGVDGTGLTAIVTGASSGIGVETARVLSLRGVHVVMAVRNTDSGAKVKEDIVKQVPGAKLDV 84

  Fly    99 RQLDLCSMKSIRNFAAGFKREQNKLHILINNAGIMDCPKMLTEDGFEMQIGVNHMGHFLLTLLLL 163
            .:|||.||:|:|.||:.:|.....|::||||||||.||.||::|..|:|...||:||||||.|||
plant    85 MELDLSSMQSVRKFASEYKSTGLPLNLLINNAGIMACPFMLSKDNIELQFATNHLGHFLLTKLLL 149

  Fly   164 DVLKSSA-----PSRVVVLSSIAHRFG---RIKRDDLNSEKSYDRKMAYCQSKLANVLFTRELAK 220
            |.:||::     ..|:|.|||.||||.   .::.|.:|.:.||....||.||||.|||...||.|
plant   150 DTMKSTSRESKREGRIVNLSSEAHRFSYPEGVRFDKINDKSSYSSMRAYGQSKLCNVLHANELTK 214

  Fly   221 RL--SGTGVTVNALHPGVVNTELFRN-TPFLGSWFGKLLIAPIIWIFIKTARNGAQTTLYAALDP 282
            :|  .|..:|.|:||||.:.|.|.|. .|:|.     :.:..:....:|:...||.||.|.||:|
plant   215 QLKEDGVNITANSLHPGAIMTNLGRYFNPYLA-----VAVGAVAKYILKSVPQGAATTCYVALNP 274

  Fly   283 SLEKVSGRYFSDCKQKHVGSAAQYDDDAQFLWAESEKWT 321
            .:..|||.||.|..........:..:.|:.:|..|.|.|
plant   275 QVAGVSGEYFQDSNIAKPLPLVKDTELAKKVWDFSTKLT 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2070	NP_001260786.1	PRK06197	41..323	CDD:235737	119/292 (41%)
CG2070	NP_001260786.1	NADB_Rossmann	43..317	CDD:304358	115/284 (40%)
Tic32-IVa	NP_849428.1	retinol-DH_like_SDR_c_like	29..306	CDD:212492	114/281 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I1212
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D921996at2759
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm1091
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780