Protein Alignment CG2070 and DHRS12

DIOPT Version :9

• Sequence 1: NP_001260786.1
• Gene: CG2070 / 35706
• FlyBaseID: FBgn0033203
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_001364858.1
• Gene: DHRS12 / 79758
• HGNCID: 25832
• Length: 320
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 90/224 - (40%)
• Similarity: 126/224 - (56%)
• Gaps: 13/224 - (5%)

  Fly    26 LRQYMQGG------QFTTKTNET---GRVAIVTGCNQGIGKETVLELARRGATVYMACRDMKKCE 81
            ||:|.:.|      .|.....|.   |||.:|||.|.||||.|.||:|:||.||::.|||....|
Human    14 LREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAE 78

  Fly    82 NARREIIKATNNQNIFARQLDLCSMKSIRNFAAGFKREQNKLHILINNAGIMDCPKMLTEDGFEM 146
            :||.|||:.:.|||||...:||...|.|..|...||:| :|||:||||||.|...:.|||||.|.
Human    79 DARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFKQE-HKLHVLINNAGCMVNKRELTEDGLEK 142

  Fly   147 QIGVNHMGHFLLTLLLLDVLKSSAPSRVVVLSSIAHRFGRIKRDDLNSEKS-YDRKMAYCQSKLA 210
            ....|.:|.::||..|:.||:.....||:.:||......::..:||.||:: :|..|.|.|:|..
Human   143 NFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQ 207

  Fly   211 NVLFTRELAKRLSGTGVTVNALHPGVVNT 239
            .|:.|...|:  ....:..:::|||..:|
Human   208 QVVLTERWAQ--GHPAIHFSSMHPGWADT 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2070	NP_001260786.1	PRK06197	41..323	CDD:235737	85/203 (42%)
		NADB_Rossmann	43..317	CDD:304358	84/198 (42%)
DHRS12	NP_001364858.1	NADB_Rossmann	40..>235	CDD:419666	84/198 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2072
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.760