Protein Alignment CG2070 and Dhrs13

DIOPT Version :10

• Sequence 1: NP_610308.2
• Gene: CG2070 / 35706
• FlyBaseID: FBgn0033203
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_899109.2
• Gene: Dhrs13 / 70451
• MGIID: 1917701
• Length: 376
• Species: Mus musculus
• Alignment Length: 321
• Identity: 139/321 - (43%)
• Similarity: 194/321 - (60%)
• Gaps: 20/321 - (6%)

  Fly    12 LAYGSALSAIGIYLLRQY------MQGGQFTTKTNETGRVAIVTGCNQGIGKETVLELARRGATV 70
            |..|:.| .:|.|:|..|      ..||..:.:    ||..:|||.|.||||.|.||||||||.|
Mouse     4 LLLGAGL-LLGAYVLVYYNLVKAPSCGGIGSLR----GRTVVVTGANSGIGKMTALELARRGARV 63

  Fly    71 YMACRDMKKCENARREIIKATNNQNIFARQLDLCSMKSIRNFAAGFKREQNKLHILINNAGIMDC 135
            .:|||..::.|.|..::.:.:.|..:....|||.|:.|::.||..|...:.:|.:||:||||..|
Mouse    64 VLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVQAFATAFLSSEPRLDVLIHNAGISSC 128

  Fly   136 PKMLTEDGFEMQIGVNHMGHFLLTLLLLDVLKSSAPSRVVVLSSIAHRFGRIKRDDLNSE-KSYD 199
            .:  |.:.|.:.:.|||:|.||||.|||..|:|.||||||::||.|||.||:....|:.. ..:.
Mouse   129 GR--TRETFNLLLRVNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRRGRLDFTRLDCPVVGWQ 191

  Fly   200 RKM-AYCQSKLANVLFTRELAKRLSGTGVTVNALHPGVVNTELF-RNTPFLGSWFGKLLIAPIIW 262
            ::: ||..||||||||.||||.:|.|||||..|.|||.||:||| |:.|   .|. :.::.|:.|
Mouse   192 QELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHLP---GWL-RPILRPLAW 252

  Fly   263 IFIKTARNGAQTTLYAALDPSLEKVSGRYFSDCKQKHVGSAAQYDDDAQFLWAESEKWTGI 323
            :.::..:.||||.||.||...:|.:|||||::|..:.|..||:.|..||.||..::|..|:
Mouse   253 LVLRAPQGGAQTPLYCALQEGIEPLSGRYFANCHVEEVSPAARDDQAAQRLWKATKKLAGL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2070	NP_610308.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	128/276 (46%)
Dhrs13	NP_899109.2	retinol-DH_like_SDR_c_like	36..304	CDD:212492	126/273 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	311..376		1/3 (33%)