DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2070 and rdh14

DIOPT Version :9

Sequence 1:	NP_001260786.1	Gene:	CG2070 / 35706	FlyBaseID:	FBgn0033203	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_001017231.1	Gene:	rdh14 / 549985	XenbaseID:	XB-GENE-1018384	Length:	323	Species:	Xenopus tropicalis

Alignment Length:	330	Identity:	155/330 - (46%)
Similarity:	201/330 - (60%)	Gaps:	20/330 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SAPTDYLFCPLAYGSALSAIGIYLLRQYMQ-GGQFTTKTNETGRVAIVTGCNQGIGKETVLELAR 65
            |:|...:...:|.|..|..:...||...:: ||....:    |:..|:||.|.||||.|..||.:
Frog     4 SSPALMVAAAVALGGGLILVVRRLLSNSVRAGGSGLMR----GKTVIITGANCGIGKATAAELVK 64

  Fly    66 RGATVYMACRDMKKCENARREIIK-ATNNQNIFARQLDLCSMKSIRNFAAGFKREQNKLHILINN 129
            :.|.|.:||||..:.|.|..|:.: |.....|..:||||.|::|:|.|.....:|:.:|.:||||
Frog    65 QEARVILACRDQGRAEEAAAELRREAGERGEIVIKQLDLGSLQSVRRFCQEVLKEEPRLDVLINN 129

  Fly   130 AGIMDCPKMLTEDGFEMQIGVNHMGHFLLTLLLLDVLKSSAPSRVVVLSSIAHRFGRIKRDDLNS 194
            ||:..||...||||||||.||||:||||||..||.:||||||||:||:||..:::|.|..|||||
Frog   130 AGVFQCPYTKTEDGFEMQFGVNHLGHFLLTHHLLGLLKSSAPSRIVVVSSKLYKYGEINFDDLNS 194

  Fly   195 EKSYDRKMAYCQSKLANVLFTRELAKRLSGTGVTVNALHPGVVNTELFR--NTPFLGSWFGKLLI 257
            ||||.|...|.:|||||:|||||||.||.||||||||||||:|.|.|.|  |.|        :||
Frog   195 EKSYSRSFGYSRSKLANILFTRELASRLEGTGVTVNALHPGIVRTNLGRHINIP--------ILI 251

  Fly   258 APII----WIFIKTARNGAQTTLYAALDPSLEKVSGRYFSDCKQKHVGSAAQYDDDAQFLWAESE 318
            .|:.    |.|.|:...||||::|.|..|.:|.|||.||.:.|::.:...|..|..|:.||..||
Frog   252 KPLFNVVSWAFFKSPEEGAQTSIYLASSPEVEGVSGSYFGNSKEEELLPKAMDDLVARKLWDISE 316

  Fly   319 KWTGI 323
            ...|:
Frog   317 VMVGL 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2070	NP_001260786.1	PRK06197	41..323	CDD:235737	145/288 (50%)
CG2070	NP_001260786.1	NADB_Rossmann	43..317	CDD:304358	143/280 (51%)
rdh14	NP_001017231.1	NADB_Rossmann	42..315	CDD:389744	143/280 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960