DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2070 and rdh13

DIOPT Version :9

Sequence 1:	NP_001260786.1	Gene:	CG2070 / 35706	FlyBaseID:	FBgn0033203	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_001011000.1	Gene:	rdh13 / 496409	XenbaseID:	XB-GENE-965068	Length:	329	Species:	Xenopus tropicalis

Alignment Length:	306	Identity:	161/306 - (52%)
Similarity:	205/306 - (66%)	Gaps:	3/306 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GSALSAIGIYLLRQYMQGGQFTTKTNETGRVAIVTGCNQGIGKETVLELARRGATVYMACRDMKK 79
            |:||.  |..||:.|..||...:|.:..|:..||||.|.||||||.||||:||..:.||||||.|
Frog    12 GTALG--GAILLKDYTGGGNCPSKASIIGQTVIVTGANTGIGKETALELAKRGGRIIMACRDMGK 74

  Fly    80 CENARREIIKATNNQNIFARQLDLCSMKSIRNFAAGFKREQNKLHILINNAGIMDCPKMLTEDGF 144
            ||||.|:|...|.|.|:|||.|||.|.|||:.||.....|:.::.:|||||.:|.||...|||.|
Frog    75 CENAARDIRGKTLNHNVFARHLDLASSKSIKEFAKTIINEEERVDVLINNAAVMRCPHWKTEDNF 139

  Fly   145 EMQIGVNHMGHFLLTLLLLDVLKSSAPSRVVVLSSIAHRFGRIKRDDLNSE-KSYDRKMAYCQSK 208
            |||.||||:||||||.|||:.:|.|..||::.:||:||..|.|..||||.| |.|:.|.||||||
Frog   140 EMQFGVNHLGHFLLTNLLLEKMKRSENSRIINVSSLAHIAGDIDFDDLNWEKKKYNTKAAYCQSK 204

  Fly   209 LANVLFTRELAKRLSGTGVTVNALHPGVVNTELFRNTPFLGSWFGKLLIAPIIWIFIKTARNGAQ 273
            |||||||.||||||.||.:|.|:|||||.:|||.|:|....|.|...::||:.|..:|:.:..||
Frog   205 LANVLFTNELAKRLQGTKLTANSLHPGVADTELGRHTGMHQSAFSSTILAPLFWFLVKSPKQAAQ 269

  Fly   274 TTLYAALDPSLEKVSGRYFSDCKQKHVGSAAQYDDDAQFLWAESEK 319
            .::|.|:..:|:.|||:||:..|:|.....|..::.|:.||.||.|
Frog   270 PSVYLAVAENLQGVSGKYFNALKEKEPAPQALDEESARKLWEESAK 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2070	NP_001260786.1	PRK06197	41..323	CDD:235737	151/280 (54%)
CG2070	NP_001260786.1	NADB_Rossmann	43..317	CDD:304358	148/274 (54%)
rdh13	NP_001011000.1	retinol-DH_like_SDR_c	38..313	CDD:212495	148/274 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	243	1.000	Domainoid score	I2166
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	314	1.000	Inparanoid score	I2520
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		otm48536
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060