DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2070 and Mfe2

DIOPT Version :9

Sequence 1:	NP_001260786.1	Gene:	CG2070 / 35706	FlyBaseID:	FBgn0033203	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_001285318.1	Gene:	Mfe2 / 32582	FlyBaseID:	FBgn0030731	Length:	598	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	77/314 - (24%)
Similarity:	124/314 - (39%)	Gaps:	72/314 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KTNETGRVAIVTGCNQGIGKETVLELARRGATVYMACRDM----------KKCENARREIIKATN 92
            |....||||:|||...|:|:|..|..|.|||.|.:  .|:          ::..:...:.|:...
  Fly     7 KLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVV--NDLGGTHSGDGASQRAADIVVDEIRKAG 69

  Fly    93 NQNIFARQLDLCSMKSIRNFAAGFKREQNKLHILINNAGIMDCPKML--TEDGFEMQIGVNHMGH 155
            .:.:......:...|.|......|.|    :.||:|||||:....::  :|..:.:...|:..|.
  Fly    70 GEAVADYNSVIDGAKVIETAIKAFGR----VDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGS 130

  Fly   156 FLLTLLLLDVLKSSAPSRVVVLSS---IAHRFGRIKRDDLNSEKSYDRKMAYCQSKLANVLFTRE 217
            |..|......:|.....|:::.||   |...||::.               |..:|:..:    .
  Fly   131 FKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVN---------------YTAAKMGLI----G 176

  Fly   218 LAKRLSGTGVTVNALHPGVVNTELFRNTPFL--GSWFGKL---LIAPII-----------WIFIK 266
            ||..::..|...|.|...:|.|...|.|..:  ...|.:|   ||||::           ..:|:
  Fly   177 LANTVAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAPVVAYLCHESCEDNGSYIE 241

  Fly   267 TARNGAQTTLY------AALDPSL-EKVSGRYFSD--------CKQKHVGSAAQ 305
            :|. |..|.|:      |.|.||| :.|:..|..|        .|.||:|:.|:
  Fly   242 SAA-GWATKLHMVRGKGAVLRPSLDDPVTIEYVKDVWSNVTDMSKAKHLGAIAE 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2070	NP_001260786.1	PRK06197	41..323	CDD:235737	76/311 (24%)
CG2070	NP_001260786.1	NADB_Rossmann	43..317	CDD:304358	76/309 (25%)
Mfe2	NP_001285318.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	63/274 (23%)
		PRK07791	11..248	CDD:236099	61/262 (23%)
		PLN02864	315..598	CDD:178455
		hot_dog	<383..442	CDD:294345
		HDE_HSD	471..592	CDD:239532
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930