Protein Alignment CG2070 and RDH12

DIOPT Version :9

• Sequence 1: NP_001260786.1
• Gene: CG2070 / 35706
• FlyBaseID: FBgn0033203
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_689656.2
• Gene: RDH12 / 145226
• HGNCID: 19977
• Length: 316
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 163/298 - (54%)
• Similarity: 200/298 - (67%)
• Gaps: 6/298 - (2%)

  Fly    26 LRQYMQGGQFTTKTNETGRVAIVTGCNQGIGKETVLELARRGATVYMACRDMKKCENARREIIKA 90
            :|::..||...|.....|:|.::||.|.||||||..|||.|||.||:||||:.|.|:|..||...
Human    22 IRKFFAGGVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVD 86

  Fly    91 TNNQNIFARQLDLCSMKSIRNFAAGFKREQNKLHILINNAGIMDCPKMLTEDGFEMQIGVNHMGH 155
            |.|..:..|:|||...||||.||.||..|:.:|||||||||:|.||...|.||||..:||||:||
Human    87 TKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGH 151

  Fly   156 FLLTLLLLDVLKSSAPSRVVVLSSIAHRFGRIKRDDLNSEKSYDRKMAYCQSKLANVLFTRELAK 220
            ||||.|||:.||.|||:|||.:||:||..|:|...||.|||.|.|..|||.||||||||||||||
Human   152 FLLTYLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAK 216

  Fly   221 RLSGTGVTVNALHPGVVNTELFRNTPFLGSWFGKLLIAPIIWIFIKTARNGAQTTLYAALDPSLE 285
            ||.|||||..|:|||||.:||.|::..|      .|:..:...|:||||.||||:|:.||...||
Human   217 RLQGTGVTTYAVHPGVVRSELVRHSSLL------CLLWRLFSPFVKTAREGAQTSLHCALAEGLE 275

  Fly   286 KVSGRYFSDCKQKHVGSAAQYDDDAQFLWAESEKWTGI 323
            .:||:||||||:..|...|:.:..|:.||..|.:..||
Human   276 PLSGKYFSDCKRTWVSPRARNNKTAERLWNVSCELLGI 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2070	NP_001260786.1	PRK06197	41..323	CDD:235737	157/281 (56%)
		NADB_Rossmann	43..317	CDD:304358	156/273 (57%)
RDH12	NP_689656.2	retinol-DH_like_SDR_c	39..307	CDD:212495	156/273 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2072
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		otm41333
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.770