Protein Alignment CG30491 and DHRS12

DIOPT Version :9

• Sequence 1: NP_001260784.1
• Gene: CG30491 / 35704
• FlyBaseID: FBgn0050491
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_001364858.1
• Gene: DHRS12 / 79758
• HGNCID: 25832
• Length: 320
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 95/258 - (36%)
• Similarity: 137/258 - (53%)
• Gaps: 41/258 - (15%)

  Fly     1 MSLFAFLKSRTAFWLSFTGTTTGLAFFVKDLMQGGQFTKETNET---------------GKVFIV 50
            |||:     |:..|            |.|.|.   ::||...|:               |:||:|
Human     1 MSLY-----RSVVW------------FAKGLR---EYTKSGYESACKDFVPHDLEVQIPGRVFLV 45

  Fly    51 TGANTGIGKETVREIAKRGGTVYMACRNLKKCEEAREEIVLETKNKYVYCRQCDLASQESIRHFV 115
            ||.|:||||.|..|||||||||::.||:....|:||.||:.|:.|:.::....||:..:.|..||
Human    46 TGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFV 110

  Fly   116 AAFKREQEH-LHVLINNAGVMRCPRSLTSDGIELQLGVNHMGHFLLTNLLLDLLKKSSPSRIVNV 179
            ..||  ||| |||||||||.|...|.||.||:|.....|.:|.::||..|:.:|:|....|::.|
Human   111 ENFK--QEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITV 173

  Fly   180 SSLAHTRGEINTGDLNSDKS-YDEGKAYSQSKLANVLFTRELAKRLEGTNVTANALHPGVVDT 241
            ||......::||.||.|::: :|....|:|:|...|:.|...|:....  :..:::|||..||
Human   174 SSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPA--IHFSSMHPGWADT 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_001260784.1	PRK06197	43..323	CDD:235737	85/216 (39%)
		NADB_Rossmann	45..319	CDD:304358	84/199 (42%)
DHRS12	NP_001364858.1	NADB_Rossmann	40..>235	CDD:419666	84/199 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810