Protein Alignment CG30491 and RDH14

DIOPT Version :9

• Sequence 1: NP_001260784.1
• Gene: CG30491 / 35704
• FlyBaseID: FBgn0050491
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_065956.1
• Gene: RDH14 / 57665
• HGNCID: 19979
• Length: 336
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 155/329 - (47%)
• Similarity: 201/329 - (61%)
• Gaps: 35/329 - (10%)

  Fly    12 AFWLS---FTGTTTGLAFFVKDLMQGGQFTKETNETGKVFIVTGANTGIGKETVREIAKRGGTVY 73
            |.||:   |.|..      |:.|.:||.   .....||..::||||:|:|:.|..|:.:.|..|.
Human    16 ALWLAARRFVGPR------VQRLRRGGD---PGLMHGKTVLITGANSGLGRATAAELLRLGARVI 71

  Fly    74 MACRNLKKCEEAREEIVLETKNK-------------YVYCRQCDLASQESIRHFVAAFKREQEHL 125
            |.||:..:.|||..::..|.:..             .:..|:.||||..|:|.|.....:|:..|
Human    72 MGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRL 136

  Fly   126 HVLINNAGVMRCPRSLTSDGIELQLGVNHMGHFLLTNLLLDLLKKSSPSRIVNVSSLAHTRGEIN 190
            .|||||||:.:||...|.||.|:|.||||:||||||||||.|||.|:|||||.|||..:..|:||
Human   137 DVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDIN 201

  Fly   191 TGDLNSDKSYDEGKAYSQSKLANVLFTRELAKRLEGTNVTANALHPGVVDTEIIRHMGFFNNFFA 255
            ..||||::||::...||:|||||:|||||||:||||||||.|.||||:|.|.:.||:      ..
Human   202 FDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHI------HI 260

  Fly   256 GLFVKPLF----WPFVKTPRNGAQTSLYVALDPELEKVTGQYFSDCKLKEMAPAATDTQTAKWLW 316
            .|.|||||    |.|.|||..|||||:|:|..||:|.|:|:||.|||.:|:.|.|.|...|:.||
Human   261 PLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLW 325

  Fly   317 AVSE 320
            .:||
Human   326 DISE 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_001260784.1	PRK06197	43..323	CDD:235737	146/295 (49%)
		NADB_Rossmann	45..319	CDD:304358	144/290 (50%)
RDH14	NP_065956.1	retinol-DH_like_SDR_c	43..328	CDD:212495	144/290 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8851
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.750