DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30491 and rdh14

DIOPT Version :9

Sequence 1:	NP_001260784.1	Gene:	CG30491 / 35704	FlyBaseID:	FBgn0050491	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001017231.1	Gene:	rdh14 / 549985	XenbaseID:	XB-GENE-1018384	Length:	323	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	151/308 - (49%)
Similarity:	192/308 - (62%)	Gaps:	20/308 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GLAFFVKDLMQ-----GGQFTKETNETGKVFIVTGANTGIGKETVREIAKRGGTVYMACRNLKKC 82
            ||...|:.|:.     ||.....    ||..|:||||.||||.|..|:.|:...|.:|||:..:.
Frog    19 GLILVVRRLLSNSVRAGGSGLMR----GKTVIITGANCGIGKATAAELVKQEARVILACRDQGRA 79

  Fly    83 EEAREEIVLETKNK-YVYCRQCDLASQESIRHFVAAFKREQEHLHVLINNAGVMRCPRSLTSDGI 146
            |||..|:..|...: .:..:|.||.|.:|:|.|.....:|:..|.||||||||.:||.:.|.||.
Frog    80 EEAAAELRREAGERGEIVIKQLDLGSLQSVRRFCQEVLKEEPRLDVLINNAGVFQCPYTKTEDGF 144

  Fly   147 ELQLGVNHMGHFLLTNLLLDLLKKSSPSRIVNVSSLAHTRGEINTGDLNSDKSYDEGKAYSQSKL 211
            |:|.||||:||||||:.||.|||.|:|||||.|||..:..||||..||||:|||.....||:|||
Frog   145 EMQFGVNHLGHFLLTHHLLGLLKSSAPSRIVVVSSKLYKYGEINFDDLNSEKSYSRSFGYSRSKL 209

  Fly   212 ANVLFTRELAKRLEGTNVTANALHPGVVDTEIIRHMGFFNNFFAGLFVKPLF----WPFVKTPRN 272
            ||:|||||||.|||||.||.||||||:|.|.:.||:..      .:.:||||    |.|.|:|..
Frog   210 ANILFTRELASRLEGTGVTVNALHPGIVRTNLGRHINI------PILIKPLFNVVSWAFFKSPEE 268

  Fly   273 GAQTSLYVALDPELEKVTGQYFSDCKLKEMAPAATDTQTAKWLWAVSE 320
            |||||:|:|..||:|.|:|.||.:.|.:|:.|.|.|...|:.||.:||
Frog   269 GAQTSIYLASSPEVEGVSGSYFGNSKEEELLPKAMDDLVARKLWDISE 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_001260784.1	PRK06197	43..323	CDD:235737	145/283 (51%)
CG30491	NP_001260784.1	NADB_Rossmann	45..319	CDD:304358	143/278 (51%)
rdh14	NP_001017231.1	NADB_Rossmann	42..315	CDD:389744	143/278 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960