Sequence 1: | NP_001260784.1 | Gene: | CG30491 / 35704 | FlyBaseID: | FBgn0050491 | Length: | 331 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_057457.1 | Gene: | WWOX / 51741 | HGNCID: | 12799 | Length: | 414 | Species: | Homo sapiens |
Alignment Length: | 339 | Identity: | 128/339 - (37%) |
---|---|---|---|
Similarity: | 183/339 - (53%) | Gaps: | 43/339 - (12%) |
- Green bases have known domain annotations that are detailed below.
Fly 6 FLKSRTAFWLS-----------FTGTTTGLAFFVKDLMQGGQFTKETNETGKVFIVTGANTGIGK 59
Fly 60 ETVREIAKRGGTVYMACRNLKKCEEAREEIVLETKNKYVYCRQCDLASQESIRHFVAAFKREQEH 124
Fly 125 LHVLINNAGVMRCPRSLTSDGIELQLGVNHMGHFLLTNLLLDLLKKSSPSRIVNVSSLAHTRGEI 189
Fly 190 N--TGDLN------SDKSYDEGKAYSQSKLANVLFTRELAKRLEGTNVTANALHPGVVDTEIIRH 246
Fly 247 MGFFNNFFAGLFVKPLFW----PFVKTPRNGAQTSLYVALDPELEKVTGQYFSDCKLKEMAPAAT 307
Fly 308 DTQTAKWLWAVSEK 321 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CG30491 | NP_001260784.1 | PRK06197 | 43..323 | CDD:235737 | 118/291 (41%) |
NADB_Rossmann | 45..319 | CDD:304358 | 115/285 (40%) | ||
WWOX | NP_057457.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..23 | ||
WW | 19..47 | CDD:238122 | |||
Nuclear localization signal. /evidence=ECO:0000250 | 50..55 | ||||
WW | 60..90 | CDD:238122 | 1/4 (25%) | ||
human_WWOX_like_SDR_c-like | 124..407 | CDD:187669 | 117/289 (40%) | ||
Interaction with MAPT. /evidence=ECO:0000250 | 125..414 | 116/288 (40%) | |||
Mediates targeting to the mitochondria. /evidence=ECO:0000250 | 209..273 | 29/63 (46%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E2759_KOG1208 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000061 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100091 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X72 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
5 | 4.710 |