Protein Alignment CG30491 and HSD17B7

DIOPT Version :9

• Sequence 1: NP_001260784.1
• Gene: CG30491 / 35704
• FlyBaseID: FBgn0050491
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_057455.1
• Gene: HSD17B7 / 51478
• HGNCID: 5215
• Length: 341
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 70/304 - (23%)
• Similarity: 116/304 - (38%)
• Gaps: 73/304 - (24%)

  Fly    46 KVFIVTGANTGIGKETVREIAKRGGTVY--MACRNLKKCEEAREEIVLETKNKYVYCRQCDLASQ 108
            ||.::|||::|||....:.:......::  :||||:.|.|.....::.......|...|.|:::.
Human     3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQVDVSNL 67

  Fly   109 ESIRHFVAAFKREQEHLHVLINNAGVMRCPR------------------------------SLTS 143
            :|:.......|:..:.|..:..|||:|..|:                              .:|:
Human    68 QSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEGLLTQGDKITA 132

  Fly   144 DGIELQLGVNHMGHFLLTNLLLDLLKKS-SPSRIVNVSSLAHTRGEINTGDLNSDKSYDEGK-AY 206
            ||::.....|..|||:|...|..||..| :||:::..||.:..:...:..|....|    || .|
Human   133 DGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLEDFQHSK----GKEPY 193

  Fly   207 SQSKLANVLFTRELAKRLEGTNVTANALHPGVVDTEIIRHMGFFNNFFAGLFVKPLFW------- 264
            |.||.|..|.:..|.:......:.:|...||...|          |...|: :.|..|
Human   194 SSSKYATDLLSVALNRNFNQQGLYSNVACPGTALT----------NLTYGI-LPPFIWTLLMPAI 247

  Fly   265 --------PFVKTPRNGAQTSLYV------ALDP---ELEKVTG 291
                    .|..||.||.:..:::      :|:|   .|...||
Human   248 LLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTG 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_001260784.1	PRK06197	43..323	CDD:235737	70/304 (23%)
		NADB_Rossmann	45..319	CDD:304358	70/304 (23%)
HSD17B7	NP_057455.1	3KS_SDR_c	2..280	CDD:187645	65/291 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4278
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860