DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30491 and rdh12l

DIOPT Version :9

Sequence 1:	NP_001260784.1	Gene:	CG30491 / 35704	FlyBaseID:	FBgn0050491	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001009912.1	Gene:	rdh12l / 494176	ZFINID:	ZDB-GENE-040801-48	Length:	291	Species:	Danio rerio

Alignment Length:	281	Identity:	149/281 - (53%)
Similarity:	197/281 - (70%)	Gaps:	17/281 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GKVFIVTGANTGIGKETVREIAKRGGTVYMACRNLKKCEEAREEIVLETKNKYVYCRQCDLASQE 109
            ||..::|||||||||||..::||||..:.||||:::|.|.|.:|:...:.|:.|:....||:..:
Zfish    13 GKTVLITGANTGIGKETAIDLAKRGARIIMACRDMEKAEAALKEVKDSSGNQDVFISSLDLSDSK 77

  Fly   110 SIRHFVAAFKREQEHLHVLINNAGVMRCPRSLTSDGIELQLGVNHMGHFLLTNLLLDLLKKSSPS 174
            |||.|.....:|::.:::||||||||.||...|:||.|:|:|||||||||||.|||||:|:|:|:
Zfish    78 SIRGFAEKINKEEKQVNILINNAGVMVCPYGKTADGFEMQIGVNHMGHFLLTYLLLDLIKRSAPA 142

  Fly   175 RIVNVSSLAHTRGEINTGDLNSDKSYDEGKAYSQSKLANVLFTRELAKRLEGTNVTANALHPGVV 239
            ||:||||.||..|.||..|:||:|:||:.|||.|||||||||||.||||||||.|||.:||||||
Zfish   143 RIINVSSTAHQWGTINLEDINSEKNYDKQKAYCQSKLANVLFTRSLAKRLEGTGVTAYSLHPGVV 207

  Fly   240 DTEIIRHMGFFNNFFAGLFVKP---LFW---PFVKTPRNGAQTSLYVALDPELEKVTGQYFSDCK 298
            .|::.||:.           ||   :.|   ||.||...|||||:|.|:||.|:..:|:|:|||.
Zfish   208 QTDLWRHLS-----------KPQQAVMWFTKPFTKTSVQGAQTSIYCAVDPALQTESGKYYSDCA 261

  Fly   299 LKEMAPAATDTQTAKWLWAVS 319
            ..:.|.||.|.:.|:.||.:|
Zfish   262 PAKAAKAAMDDEVAQRLWELS 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_001260784.1	PRK06197	43..323	CDD:235737	149/281 (53%)
CG30491	NP_001260784.1	NADB_Rossmann	45..319	CDD:304358	148/279 (53%)
rdh12l	NP_001009912.1	PRK06197	5..291	CDD:235737	149/281 (53%)
rdh12l	NP_001009912.1	NADB_Rossmann	13..282	CDD:304358	148/279 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	254	1.000	Domainoid score	I2017
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2630
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm6476
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.740