DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30491 and rdh12

DIOPT Version :9

Sequence 1:	NP_001260784.1	Gene:	CG30491 / 35704	FlyBaseID:	FBgn0050491	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001002325.1	Gene:	rdh12 / 436597	ZFINID:	ZDB-GENE-040718-9	Length:	319	Species:	Danio rerio

Alignment Length:	292	Identity:	152/292 - (52%)
Similarity:	196/292 - (67%)	Gaps:	6/292 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VKDLMQGGQFTKETNETGKVFIVTGANTGIGKETVREIAKRGGTVYMACRNLKKCEEAREEIVLE 92
            ::....||.........|||.:|||||:||||||..::|.||..|.:|||:|:|.|||..||...
Zfish    25 IRKYAAGGSCRSTVRLDGKVALVTGANSGIGKETALDLASRGARVILACRDLEKAEEAAAEIRTR 89

  Fly    93 TKNKYVYCRQCDLASQESIRHFVAAFKREQEHLHVLINNAGVMRCPRSLTSDGIELQLGVNHMGH 157
            .....|..|:.|||...|||.|...|.||.:|||:||||||||.||...|:||.|:|:||||:||
Zfish    90 VGGAKVEVRELDLADCCSIRAFAQRFLREVDHLHILINNAGVMMCPYMKTADGFEMQIGVNHLGH 154

  Fly   158 FLLTNLLLDLLKKSSPSRIVNVSSLAHTRGEINTGDLNSDKSYDEGKAYSQSKLANVLFTRELAK 222
            :|||.||:.|||:|:|||||.||||||..|.|...||:|..||:.|.||.||||||||||||||:
Zfish   155 YLLTYLLIGLLKRSAPSRIVVVSSLAHNFGWIRFHDLHSQGSYNSGLAYCQSKLANVLFTRELAR 219

  Fly   223 RLEGTNVTANALHPGVVDTEIIRHMGFFNNFFAGLFVKPLFWPFVKTPRNGAQTSLYVALDPELE 287
            ||:|:|||.|::|||.|.:|::||....:..||      .|..|:|:|:.|||||:|.|:..||:
Zfish   220 RLQGSNVTVNSVHPGTVRSELVRHSTLMSLLFA------FFSMFLKSPKEGAQTSIYCAVAEELQ 278

  Fly   288 KVTGQYFSDCKLKEMAPAATDTQTAKWLWAVS 319
            .::|::||||....:||.....:||:.||.||
Zfish   279 SISGKHFSDCAPAFVAPQGRSEETARKLWDVS 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_001260784.1	PRK06197	43..323	CDD:235737	150/277 (54%)
CG30491	NP_001260784.1	NADB_Rossmann	45..319	CDD:304358	148/273 (54%)
rdh12	NP_001002325.1	PRK06197	41..318	CDD:235737	150/276 (54%)
rdh12	NP_001002325.1	NADB_Rossmann	42..310	CDD:304358	148/273 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm6476
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	LDO	PTHR24320
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.820