DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30491 and si:ch211-107o10.3

DIOPT Version :9

Sequence 1:	NP_001260784.1	Gene:	CG30491 / 35704	FlyBaseID:	FBgn0050491	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001186229.1	Gene:	si:ch211-107o10.3 / 407663	ZFINID:	ZDB-GENE-030131-4716	Length:	327	Species:	Danio rerio

Alignment Length:	308	Identity:	154/308 - (50%)
Similarity:	207/308 - (67%)	Gaps:	8/308 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FTGTT----TGLAFF-VKDLMQGGQFTKETNETGKVFIVTGANTGIGKETVREIAKRGGTVYMAC 76
            :||.|    ||:..| .:..:.||....:....||..::||.||||||||..::||||..|.:||
Zfish    16 YTGVTFVLITGVGLFGFRRWLAGGVCRSKARLDGKTVLITGGNTGIGKETAVDMAKRGARVILAC 80

  Fly    77 RNLKKCEEAREEIVLETKNKYVYCRQCDLASQESIRHFVAAFKREQEHLHVLINNAGVMRCPRSL 141
            |::.:..:|.|||...:.|:.|..:..||||.:|:|..|...::.::.|.:||||||||.||:..
Zfish    81 RDMSRAHKAAEEIRKRSGNENVTVKMLDLASLQSVRDLVKDVQQSEQRLDILINNAGVMMCPKWH 145

  Fly   142 TSDGIELQLGVNHMGHFLLTNLLLDLLKKSSPSRIVNVSSLAHTRGEINTGDLNSDKSYDEGKAY 206
            |.:|.|:|:||||:||||||||||||||||:|||||||:|:||.||:||..|:|.||.||..::|
Zfish   146 TDEGFEMQIGVNHLGHFLLTNLLLDLLKKSAPSRIVNVASVAHERGKINFNDINMDKDYDPYQSY 210

  Fly   207 SQSKLANVLFTRELAKRLEGTNVTANALHPGVVDTEIIRHMGFFNNFFAGLFVKPLFWPFVKTPR 271
            .:|||||||||||||.:|..|.||..||||||:.||:.||:  |:|.:..|.:.| |:.|.|.|.
Zfish   211 YRSKLANVLFTRELAIKLRDTGVTTYALHPGVIRTELGRHV--FSNLWRKLIILP-FYFFFKNPW 272

  Fly   272 NGAQTSLYVALDPELEKVTGQYFSDCKLKEMAPAATDTQTAKWLWAVS 319
            .||||::|.|:|..|:..:|.|:|||..||.||...|...|:.||.:|
Zfish   273 QGAQTTIYCAVDESLKHSSGLYYSDCAPKETAPQGRDDVAARRLWDLS 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_001260784.1	PRK06197	43..323	CDD:235737	146/277 (53%)
CG30491	NP_001260784.1	NADB_Rossmann	45..319	CDD:304358	145/273 (53%)
si:ch211-107o10.3	NP_001186229.1	PRK06197	48..325	CDD:235737	146/276 (53%)
si:ch211-107o10.3	NP_001186229.1	NADB_Rossmann	49..320	CDD:304358	145/273 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121782
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2630
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm6476
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.740