Protein Alignment CG30491 and Hsd17b1

DIOPT Version :10

• Sequence 1: NP_610306.1
• Gene: CG30491 / 35704
• FlyBaseID: FBgn0050491
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_034605.1
• Gene: Hsd17b1 / 15485
• MGIID: 105077
• Length: 344
• Species: Mus musculus
• Alignment Length: 306
• Identity: 65/306 - (21%)
• Similarity: 105/306 - (34%)
• Gaps: 86/306 - (28%)

  Fly    47 VFIVTGANTGIGKE-TVREIAKRGGT--VYMACRNLKK------------CEEAREEIVLETKNK 96
            |.::||.::|||.. .||..:.|..:  ||...|:||.            |.....||:
Mouse     5 VVLITGCSSGIGMHLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARTQGCPPGSLEIL------ 63

  Fly    97 YVYCRQCDLASQESIRHFVAAFKREQEHLHVLINNAGVMRCPRSLTS-------DGIELQLGVNH 154
                 :.|:...:|:....|..  .:..:.||:.|||     |.|..       :.:...|.||.
Mouse    64 -----ELDVRDSKSVAAAQACV--TEGRVDVLVCNAG-----RGLFGPLEAHELNAVGAVLDVNV 116

  Fly   155 MGHFLLTNLLLDLLKKSSPSRIVNVSSLAHTRGEINTGDLNSDKSYDEGKAYSQSKLANVLFTRE 219
            :|...:....|..:|:....|::..:|:....|          ..:.|  .|..||.|.......
Mouse   117 LGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMG----------LPFHE--VYCASKFALEGLCES 169

  Fly   220 LAKRLEGTNVTANALHPGVVDTEIIRHMGFFNNFFAG---------LFVKPLFWPFVKTPRNGAQ 275
            ||..|....|..:.:..|.|      |..|:.....|         ...:.||..:::    |.:
Mouse   170 LAILLPLFGVHVSLIECGAV------HTAFYEKLVGGPGGALERADAQTRHLFAHYLR----GYE 224

  Fly   276 TSLYVALDPELEKVTG-------------QYFSDCKLKEMAPAATD 308
            .:|..|.||  |:||.             :|||..:...:|...|:
Mouse   225 QALSEAQDP--EEVTELFLTAMRAPQPALRYFSTNRFLPLARMRTE 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_610306.1	Rossmann-fold NAD(P)(+)-binding proteins	45..319	CDD:473865	65/306 (21%)
Hsd17b1	NP_034605.1	Rossmann-fold NAD(P)(+)-binding proteins	4..260	CDD:473865	63/296 (21%)