Protein Alignment CG30491 and RDH13

DIOPT Version :9

• Sequence 1: NP_001260784.1
• Gene: CG30491 / 35704
• FlyBaseID: FBgn0050491
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_001139443.1
• Gene: RDH13 / 112724
• HGNCID: 19978
• Length: 331
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 164/314 - (52%)
• Similarity: 208/314 - (66%)
• Gaps: 1/314 - (0%)

  Fly     9 SRTAFWLSFTGTTTGLAFFVKDLMQGGQFTKETNETGKVFIVTGANTGIGKETVREIAKRGGTVY 73
            ||....||..||..|.|..:||.:.||....:....||..|||||||||||:|..|:|:|||.:.
Human     2 SRYLLPLSALGTVAGAAVLLKDYVTGGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNII 66

  Fly    74 MACRNLKKCEEAREEIVLETKNKYVYCRQCDLASQESIRHFVAAFKREQEHLHVLINNAGVMRCP 138
            :|||:::|||.|.::|..||.|.:|..|..||||.:|||.|.|....|:|.:.:|||||||||||
Human    67 LACRDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCP 131

  Fly   139 RSLTSDGIELQLGVNHMGHFLLTNLLLDLLKKSSPSRIVNVSSLAHTRGEINTGDLN-SDKSYDE 202
            ...|.||.|:|.||||:|||||||||||.||.|:||||:|:|||||..|.|:..||| ..:.|:.
Human   132 HWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNT 196

  Fly   203 GKAYSQSKLANVLFTRELAKRLEGTNVTANALHPGVVDTEIIRHMGFFNNFFAGLFVKPLFWPFV 267
            ..||.|||||.||||:||::||:|:.||.|||||||..||:.||.|...:.|:...:.|:||..|
Human   197 KAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLV 261

  Fly   268 KTPRNGAQTSLYVALDPELEKVTGQYFSDCKLKEMAPAATDTQTAKWLWAVSEK 321
            |:|...||.|.|:|:..||..|:|:||...|.|..||.|.|.:.|:.|||.|.:
Human   262 KSPELAAQPSTYLAVAEELADVSGKYFDGLKQKAPAPEAEDEEVARRLWAESAR 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_001260784.1	PRK06197	43..323	CDD:235737	152/280 (54%)
		NADB_Rossmann	45..319	CDD:304358	151/274 (55%)
RDH13	NP_001139443.1	retinol-DH_like_SDR_c	38..313	CDD:212495	151/274 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	251	1.000	Domainoid score	I2108
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121782
Inparanoid	1	1.050	316	1.000	Inparanoid score	I2553
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		otm41333
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.810